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真菌性动脉瘤作为一名溺水获救儿童脑假性阿利什利菌病的致命并发症:CT表现

Mycotic aneurysms as lethal complication of brain pseudallescheriasis in a near-drowned child: a CT demonstration.

作者信息

Messori Anna, Lanza Cecilia, De Nicola Maurizio, Menichelli Francesco, Capriotti Tiziana, Morabito Letterio, Salvolini Ugo

机构信息

Neuroradiological Clinic, General Hospital Umberto I, Ancona, Italy.

出版信息

AJNR Am J Neuroradiol. 2002 Nov-Dec;23(10):1697-9.

PMID:12427626
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8185813/
Abstract

Intracranial true mycotic aneurysms are rare and generally lethal. We report a case of a near-drowned child with brain abscesses due to Pseudallescheria boydii, a saprophytic fungus, who died after subarachnoid hemorrhage occurred. CT showed contrast-enhancing lesions indicative of aneurysms of basilar and right posterior cerebral arteries that could not be appreciated 2 days before. P. boydii is often resistant to commonly used antimycotic drugs. Because CNS infection is frequently associated with near-drowning, early diagnosis and specific therapy are strongly recommended for these patients.

摘要

颅内真性真菌性动脉瘤罕见且通常致命。我们报告一例因博伊德假阿利什霉(一种腐生真菌)导致脑脓肿的近乎溺亡儿童病例,该患儿在蛛网膜下腔出血后死亡。CT显示有强化病变,提示基底动脉和右侧大脑后动脉存在动脉瘤,而两天前并未发现这些病变。博伊德假阿利什霉通常对常用抗真菌药物耐药。由于中枢神经系统感染常与近乎溺亡相关,强烈建议对这些患者进行早期诊断和特异性治疗。

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本文引用的文献

1
Endogenous Pseudallescheria boydii endophthalmitis in a patient with ring-enhancing brain lesions.一名患有环形强化脑病变患者的内源性波氏假阿利什菌眼内炎。
Ophthalmic Surg Lasers. 2001 Jul-Aug;32(4):325-9.
2
Mycotic aneurysm and cerebral infarction resulting from fungal sinusitis: imaging and pathologic correlation.真菌性鼻窦炎所致霉菌性动脉瘤和脑梗死:影像学与病理学相关性
AJNR Am J Neuroradiol. 2001 May;22(5):858-63.
3
Pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage: case report and literature review of central nervous system pseudallescheriasis.伏立康唑联合手术引流成功治疗波氏假阿利什霉脑脓肿:中枢神经系统假阿利什霉病病例报告及文献综述
Clin Infect Dis. 2000 Sep;31(3):673-7. doi: 10.1086/314042. Epub 2000 Sep 27.
4
Meningitis caused by Pseudallescheria boydii treated with voriconazole.由波氏假阿利什菌引起的脑膜炎,采用伏立康唑治疗。
Clin Infect Dis. 2000 Jun;30(6):981-2. doi: 10.1086/313817.
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7
Pathology of hyalohyphomycosis caused by Scedosporium apiospermum (Pseudallescheria boydii): an emerging mycosis.由尖端赛多孢菌(波氏假阿利什利菌)引起的透明丝孢霉病的病理学:一种新出现的真菌病。
Hum Pathol. 1998 Nov;29(11):1266-72. doi: 10.1016/s0046-8177(98)90255-6.
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Cerebral pseudallescheriasis due to Pseudallescheria boydii as the first manifestation of AIDS.
Clin Infect Dis. 1998 Jun;26(6):1476-7. doi: 10.1086/517674.
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Pseudallescheria boydii infection of the brain: imaging with pathologic confirmation.脑波氏假性阿利什利霉感染:影像检查与病理确诊
AJNR Am J Neuroradiol. 1996 Mar;17(3):589-92.
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Fatal Pseudallescheria boydii panencephalitis in a child after near-drowning.一名儿童溺水后发生致命的波氏假阿利什菌全脑炎。
Pediatr Infect Dis J. 1996 Apr;15(4):365-70. doi: 10.1097/00006454-199604000-00016.