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水痘疫苗接种8年后出现的带状疱疹性角膜葡萄膜炎和炎性高眼压症

Herpes zoster keratouveitis and inflammatory ocular hypertension 8 years after varicella vaccination.

作者信息

Lin Phoebe, Yoon Michael K, Chiu Cynthia S

机构信息

Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA.

出版信息

Ocul Immunol Inflamm. 2009 Jan-Feb;17(1):33-5. doi: 10.1080/09273940802491892.

Abstract

More than 8 years after varicella vaccination, a healthy 16 year-old boy presented with keratouveitis, severe inflammatory glaucoma in his left eye, and Hutchinson's sign. He was treated with systemic acyclovir, topical steroids, cycloplegics, and glaucoma medications for a full recovery two months after presentation. It is unclear whether the source of herpes zoster which reactivated in this patient represents wild type virus or his previous vaccine strain. Herpes zoster ophthalmicus is very rare in the pediatric population after varicella vaccination but can cause severe inflammatory glaucoma that requires aggressive therapy.

摘要

在接种水痘疫苗8年多后,一名16岁健康男孩出现了角膜葡萄膜炎、左眼严重炎性青光眼和哈钦森征。他接受了全身阿昔洛韦、局部类固醇、睫状肌麻痹剂和青光眼药物治疗,就诊两个月后完全康复。目前尚不清楚该患者重新激活的带状疱疹来源是野生型病毒还是他之前接种的疫苗株。接种水痘疫苗后,小儿眼部带状疱疹非常罕见,但可导致严重的炎性青光眼,需要积极治疗。

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