Hagelueken Gregor, Ingledew W John, Huang Hexian, Petrovic-Stojanovska Biljana, Whitfield Chris, ElMkami Hassane, Schiemann Olav, Naismith James H
Centre for Biomolecular Sciences, The University of St. Andrews, Fife KY16 9RH, UK.
Angew Chem Int Ed Engl. 2009;48(16):2904-6. doi: 10.1002/anie.200805758.
Distance fingerprinting: Pulsed electron-electron double resonance spectroscopy (PELDOR) is applied to the octameric membrane protein complex Wza of E. coli. The data yielded a detailed distance fingerprint of its periplasmic region that compares favorably to the crystal structure. These results provide the foundation to study conformation changes from interaction with partner proteins.
脉冲电子-电子双共振光谱法（PELDOR）应用于大肠杆菌的八聚体膜蛋白复合物Wza。数据产生了其周质区域的详细距离指纹图谱，与晶体结构相比具有优势。这些结果为研究与伴侣蛋白相互作用引起的构象变化奠定了基础。
