Mir Qurat Y, Ali M, Alam Prawez
Faculty of Pharmacy, Phytochemistry Research Laboratory, Department of Pharmacognosy and Phytochemistry, Hamdard University, New Delhi, India.
Nat Prod Res. 2009;23(5):422-30. doi: 10.1080/14786410802038697.
Phytochemical investigation of the stem bark of Syzygium cumini (L.) Skeels (Myrtaceae) yielded four new lignan derivatives characterised as (7alpha,8alpha,2'alpha)-3,4,5-trimethoxy-7,3',1',9'-diepoxylignan (cuminiresinol), (7alpha,7'alpha,8alpha,8'alpha)-3,4-dioxymethylene-3',4'-dimethoxy-7,9',7',9-diepoxylignan-5'-ol (5'-hydroxy-methyl-piperitol), (7alpha,7'alpha,8alpha,8'alpha)-3'-methoxy-9-oxo-7,9',7',9-diepoxylignan-3,4,4'-triol or 3-demethyl-9-oxo-pinoresinol (syzygiresinol A), (7alpha,7'alpha,8alpha,8'alpha)-9-oxo-7,9',7',9-diepoxylignan-3,4,3',4',5'-pentaol or 3,3'-didemethyl-9-oxo-pinoresinol (syzygiresinol B) along with the known lignans di-demethyl-5-hydroxypinoresinol, dimethylpinoresinol, didemethoxypinoresinol, pinoresinol and 4'-methyl-5'-hydroxypinoresinol. The structures of these lignans were elucidated on the basis of structural data analysis and chemical reactions.
对乌墨（学名：Syzygium cumini (L.) Skeels，桃金娘科）茎皮进行的植物化学研究得到了四种新的木脂素衍生物，分别鉴定为(7α,8α,2'α)-3,4,5-三甲氧基-7,3',1',9'-二环氧木脂素（乌墨树脂醇）、(7α,7'α,8α,8'α)-3,4-二氧亚甲基-3',4'-二甲氧基-7,9',7',9-二环氧木脂素-5'-醇（5'-羟基-甲基-哌立醇）、(7α,7'α,8α,8'α)-3'-甲氧基-9-氧代-7,9',7',9-二环氧木脂素-3,4,4'-三醇或3-去甲基-9-氧代-松脂醇（乌墨树脂醇A）、(7α,7'α,8α,8'α)-9-氧代-7,9',7',9-二环氧木脂素-3,4,3',4',5'-五醇或3,3'-二去甲基-9-氧代-松脂醇（乌墨树脂醇B），以及已知的木脂素双去甲基-5-羟基松脂醇、二甲基松脂醇、双去甲氧基松脂醇、松脂醇和4'-甲基-5'-羟基松脂醇。这些木脂素的结构通过结构数据分析和化学反应得以阐明。
