Liu Bo, Deng An-Jun, Yu Jin-Qian, Liu Ai-Lin, Du Guan-Hua, Qin Hai-Lin
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education and Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
J Asian Nat Prod Res. 2012;14(2):89-96. doi: 10.1080/10286020.2011.644714.
A new lignan glycoside, 7α, 7'β-bis-(4-hydroxy-3-methoxyphenyl)-7,9':7',9-diepoxylignan-8αH,8'α-O-β-d-(2″,7'α-epoxy)-glucopyranoside, named elshrugulosain (1), has been isolated from the EtOH extract of Elsholtzia rugulosa, together with six known compounds, ( - )-bornyl (E)-3,4,5-trimethoxycinnamate, apigenin, luteolin, apigenin-7-O-β-d-glucopyranoside, luteolin-7-O-β-d-glucopyranoside, and luteolin-3'-glucuronate methyl ester. Their structures were characterized by spectroscopic methods and comparison with the data in the literature. On the basis of detailed 1D and 2D NMR spectral analysis, as well as X-ray crystallographic diffraction, the NMR spectroscopic data of ( - )-bornyl (E)-3,4,5-trimethoxycinnamate were revised and assigned completely.
从糙苏香薷的乙醇提取物中分离出一种新的木脂素糖苷，7α, 7'β-双-(4-羟基-3-甲氧基苯基)-7,9':7',9-二环氧木脂素-8αH,8'α-O-β-d-(2″,7'α-环氧)-葡萄糖苷，命名为糙苏香薷苷（1），同时还分离出六种已知化合物，(-)-冰片基(E)-3,4,5-三甲氧基肉桂酸酯、芹菜素、木犀草素、芹菜素-7-O-β-d-葡萄糖苷、木犀草素-7-O-β-d-葡萄糖苷和木犀草素-3'-葡萄糖醛酸甲酯。通过光谱方法并与文献数据进行比较对它们的结构进行了表征。基于详细的一维和二维核磁共振光谱分析以及X射线晶体学衍射，对(-)-冰片基(E)-3,4,5-三甲氧基肉桂酸酯的核磁共振光谱数据进行了修订并完全归属。
