Glasser D B, Osborn D C, Nordeen J F, Min Y I
Department of Ophthalmology, University of Maryland Medical School, Baltimore.
Arch Ophthalmol. 1991 Oct;109(10):1438-40. doi: 10.1001/archopht.1991.01080100118055.
Endothelial protection (measured by vital-dye staining and computerized planimetry) and viscoelastic retention during phacoemulsification with and without traumatic lens implantation were assessed in a rabbit model comparing four viscoelastics (Healon, Amvisc Plus, Occucoat, and Viscoat). No significant differences in cell damage were noted between unoperated on controls and groups that underwent atraumatic phacoemulsification with viscoelastic. Cell damage after traumatic lens insertion was reduced significantly by all four viscoelastics. Cell damage with and without traumatic lens implantation was significantly lower when viscoelastics were retained. Viscoat and Occucoat were significantly more likely to be retained than Healon.
在兔模型中，比较了四种粘弹剂（Healon、Amvisc Plus、Occucoat和Viscoat），评估了在有或无外伤性晶状体植入的情况下进行超声乳化时的内皮保护（通过活体染料染色和计算机化平面测量法测量）和粘弹性保留情况。未手术的对照组与使用粘弹剂进行无创伤性超声乳化的组之间，未观察到细胞损伤有显著差异。所有四种粘弹剂均显著降低了外伤性晶状体植入后的细胞损伤。当保留粘弹剂时，有无外伤性晶状体植入的细胞损伤均显著降低。Viscoat和Occucoat比Healon更有可能被保留。
