神经回路形成中的瞬时细胞间相互作用。
Transient cell-cell interactions in neural circuit formation.
作者信息
Chao Daniel L, Ma Le, Shen Kang
机构信息
Neurosciences Program, Stanford University, Stanford, CA 94305, USA.
出版信息
Nat Rev Neurosci. 2009 Apr;10(4):262-71. doi: 10.1038/nrn2594.
Abstract
The wiring of the nervous system requires a complex orchestration of developmental events. Emerging evidence suggests that transient cell-cell interactions often serve as positional cues for axon guidance and synaptogenesis during the assembly of neural circuits. In contrast to the relatively stable cellular interactions between synaptic partners in mature circuits, these transient interactions involve cells that are not destined to be pre- or postsynaptic cells. Here we review the roles of these transient cell-cell interactions in a variety of developmental contexts and describe the mechanisms through which they organize neural connections.
摘要
神经系统的布线需要对发育事件进行复杂的协调。新出现的证据表明，在神经回路组装过程中，短暂的细胞间相互作用通常作为轴突导向和突触形成的位置线索。与成熟回路中突触伙伴之间相对稳定的细胞间相互作用不同，这些短暂的相互作用涉及并非注定成为突触前或突触后细胞的细胞。在这里，我们综述了这些短暂细胞间相互作用在各种发育背景下的作用，并描述了它们组织神经连接的机制。
相似文献
1
Transient cell-cell interactions in neural circuit formation.神经回路形成中的瞬时细胞间相互作用。
Nat Rev Neurosci. 2009 Apr;10(4):262-71. doi: 10.1038/nrn2594.
2
Synapse formation in developing neural circuits.发育中的神经回路中的突触形成。
Curr Top Dev Biol. 2009;87:53-79. doi: 10.1016/S0070-2153(09)01202-2.
3
Plasticity in single neuron and circuit computations.单个神经元和神经回路计算中的可塑性。
Nature. 2004 Oct 14;431(7010):789-95. doi: 10.1038/nature03011.
4
Embarrassed, but not depressed: eye opening lessons for cerebellar learning.尴尬，但不沮丧：小脑学习的启发性经验
Neuron. 2002 Jul 18;35(2):223-6. doi: 10.1016/s0896-6273(02)00771-7.
5
The motor circuit.运动回路。
Int Rev Neurobiol. 2006;69:125-67. doi: 10.1016/S0074-7742(05)69005-8.
6
Synaptic connectivity and neuronal morphology: two sides of the same coin.突触连接性与神经元形态：同一枚硬币的两面。
Neuron. 2004 Sep 2;43(5):609-17. doi: 10.1016/j.neuron.2004.08.012.
7
Put them out to pasture? What are old granule cells good for, anyway...?把它们淘汰掉？反正，衰老的颗粒细胞还有什么用呢……？
Hippocampus. 2010 Oct;20(10):1124-5. doi: 10.1002/hipo.20867.
8
The meaning of mammalian adult neurogenesis and the function of newly added neurons: the "small-world" network.哺乳动物成年神经发生的意义及新添加神经元的功能：“小世界”网络。
Med Hypotheses. 2005;64(1):114-7. doi: 10.1016/j.mehy.2004.05.013.
9
A hierarchical modeling approach of hippocampus local circuit.海马体局部回路的分层建模方法。
J Integr Neurosci. 2009 Mar;8(1):49-76. doi: 10.1142/s0219635209002083.
10
A role for circuit homeostasis in adult neurogenesis.回路稳态在成体神经发生中的作用。
Trends Neurosci. 2005 Dec;28(12):653-60. doi: 10.1016/j.tins.2005.09.007. Epub 2005 Nov 3.
引用本文的文献
1
SEMA3B switches axon-axon to axon-glia interactions required for unmyelinated axon envelopment and integrity.SEMA3B将轴突-轴突相互作用转变为无髓鞘轴突包绕和完整性所需的轴突-神经胶质细胞相互作用。
Nat Commun. 2025 Jul 1;16(1):5433. doi: 10.1038/s41467-025-61318-8.
2
Tracing Early Migratory Neurons in the Developing Nose Using Contactin-2 (Cntn2) CreERT2.使用Contactin-2（Cntn2）CreERT2追踪发育中鼻子里早期迁移的神经元。
Genesis. 2025 Aug;63(4):e70021. doi: 10.1002/dvg.70021.
3
Assembloid models of cell-cell interaction to study tissue and disease biology.细胞间相互作用的聚集体模型用于研究组织和疾病生物学。
Cell Stem Cell. 2024 Nov 7;31(11):1563-1573. doi: 10.1016/j.stem.2024.09.017. Epub 2024 Oct 24.
4
Spatiotemporal changes in Netrin/Dscam1 signaling dictate axonal projection direction in small ventral lateral clock neurons.神经导向因子/粘连蛋白 1 信号在小腹外侧时钟神经元中的时空变化决定了轴突投射方向。
Elife. 2024 Jul 25;13:RP96041. doi: 10.7554/eLife.96041.
5
Sctensor detects many-to-many cell-cell interactions from single cell RNA-sequencing data.Sctensor 可从单细胞 RNA 测序数据中检测到多对多的细胞间相互作用。
BMC Bioinformatics. 2023 Nov 7;24(1):420. doi: 10.1186/s12859-023-05490-y.
6
Self-Regulatory Neuronal Mechanisms and Long-Term Challenges in Schizophrenia Treatment.精神分裂症治疗中的自我调节神经元机制及长期挑战
Brain Sci. 2023 Apr 12;13(4):651. doi: 10.3390/brainsci13040651.
7
Chitosan Hydrogel Supplemented with Metformin Promotes Neuron-like Cell Differentiation of Gingival Mesenchymal Stem Cells.壳聚糖水凝胶联合二甲双胍促进牙龈间充质干细胞向神经元样细胞分化。
Int J Mol Sci. 2022 Mar 18;23(6):3276. doi: 10.3390/ijms23063276.
8
Microglia regulate chandelier cell axo-axonic synaptogenesis.小胶质细胞调节 Chandelier 细胞轴突-轴突突触发生。
Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2114476119. doi: 10.1073/pnas.2114476119. Epub 2022 Mar 9.
9
Improving Clinical, Cognitive, and Psychosocial Dysfunctions in Patients with Schizophrenia: A Neurofeedback Randomized Control Trial.改善精神分裂症患者的临床、认知和心理社会功能障碍：一项神经反馈随机对照试验。
Neural Plast. 2021 Aug 12;2021:4488664. doi: 10.1155/2021/4488664. eCollection 2021.
10
Caged Cumate Enables Proximity-Dependent Control Over Gene Expression.笼型 cumate 可实现对基因表达的邻近依赖性控制。
Chembiochem. 2021 Jul 15;22(14):2440-2448. doi: 10.1002/cbic.202100158. Epub 2021 Jun 8.
本文引用的文献
1
UNC-6/netrin and its receptor UNC-5 locally exclude presynaptic components from dendrites.UNC-6/网蛋白及其受体UNC-5在局部将突触前成分排除在树突之外。
Nature. 2008 Oct 2;455(7213):669-73. doi: 10.1038/nature07291.
2
Retinal axon growth at the optic chiasm: to cross or not to cross.视网膜轴突在视交叉处的生长：交叉还是不交叉。
Annu Rev Neurosci. 2008;31:295-315. doi: 10.1146/annurev.neuro.31.060407.125609.
3
Building a synapse: lessons on synaptic specificity and presynaptic assembly from the nematode C. elegans.构建突触：从秀丽隐杆线虫中汲取的关于突触特异性和突触前组装的经验教训。
Curr Opin Neurobiol. 2008 Feb;18(1):69-76. doi: 10.1016/j.conb.2008.04.003. Epub 2008 Jun 4.
4
mls-2 and vab-3 Control glia development, hlh-17/Olig expression and glia-dependent neurite extension in C. elegans.mls-2和vab-3调控秀丽隐杆线虫中的神经胶质细胞发育、hlh-17/Olig表达以及神经胶质细胞依赖的神经突延伸。
Development. 2008 Jul;135(13):2263-75. doi: 10.1242/dev.019547. Epub 2008 May 28.
5
Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion.Robo3轴突导向受体的可变剪接控制着中线从吸引到排斥的转变。
Neuron. 2008 May 8;58(3):325-32. doi: 10.1016/j.neuron.2008.02.016.
6
Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites.伯格曼胶质细胞和识别分子CHL1组织GABA能轴突并引导浦肯野细胞树突的神经支配。
PLoS Biol. 2008 Apr 29;6(4):e103. doi: 10.1371/journal.pbio.0060103.
7
Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans.在秀丽隐杆线虫中，神经胶质细胞通过UNC-6（netrin）信号传导促进局部突触形成。
Science. 2007 Oct 5;318(5847):103-6. doi: 10.1126/science.1143762.
8
Pathfinding by peripheral pioneer neurons in grasshoppers.在蝗虫中，由外围先驱神经元进行的路径寻找。
Science. 1982 Dec 10;218(4577):1082-8. doi: 10.1126/science.218.4577.1082.
9
Wnt signaling positions neuromuscular connectivity by inhibiting synapse formation in C. elegans.在秀丽隐杆线虫中，Wnt信号通路通过抑制突触形成来定位神经肌肉连接。
Cell. 2007 Aug 24;130(4):704-16. doi: 10.1016/j.cell.2007.06.046.
10
Boc is a receptor for sonic hedgehog in the guidance of commissural axons.Boc是连合轴突导向中声波刺猬蛋白的一种受体。
Nature. 2006 Nov 16;444(7117):369-73. doi: 10.1038/nature05246. Epub 2006 Nov 1.
Zotero 插件