Iwakiri Akira, Ganmyo Hidenari, Yamamoto Seigo, Otao Kayoko, Mikasa Mieko, Kizoe Sigeko, Katayama Kazuhiko, Wakita Takaji, Takeda Naokazu, Oka Tomoichiro
Miyazaki Prefectural Institute for Public Health and Environment, Japan.
Arch Virol. 2009;154(4):689-93. doi: 10.1007/s00705-009-0358-0. Epub 2009 Mar 20.
Sapovirus (SaV) is an important pathogen causing gastroenteritis in humans. Quantitative analysis of the viral loads in feces collected from two SaV outbreaks was performed. Our results showed that SaV excretion generally decreased to an undetectable level in 2 weeks; however, some individuals excrete SaV in feces at high concentrations for 2-4 weeks after the onset of illness. In addition, we identified for the first time nucleotide changes in the capsid region during prolonged excretion.
