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[通过弥散加权成像诊断的感染性硬膜下血肿病例]

[Case of infected subdural hematoma diagnosed by diffusion-weighted imaging].

作者信息

Narita Eriko, Maruya Jun, Nishimaki Keiichi, Heianna Joichi, Miyauchi Takaharu, Nakahata Jun-ichi, Kitahara Hiroshi, Minakawa Takashi

机构信息

Department of Neurosurgery, Akita Red Cross Hospital, 222-1 Nawashirosawa, Saruta, Kamikitate, Akita 010-1495, Japan.

出版信息

Brain Nerve. 2009 Mar;61(3):319-23.

Abstract

An 80-year-old man who had undergone total gastrectomy and splenectomy for gastric cancer 13 years ago presented with headache, drowsiness, and high fever 1 month after a traffic accident. Brain CT scans revealed bilateral subdural fluid collections. Diffusion-weighted imaging (DWI) showed mixed high and low signal intensities in the left subdural fluid, and contrast-enhanced MR imaging revealed capsule enhancement of the left subdural fluid collection. The patient was diagnosed with left subdural empyema, and 2 burr-holes were drilled for drainage and irrigation. Operative findings revealed a neomembrane underneath the dura mater. Old hematoma and yellowish-white purulent fluid were present within the neomembrane. This confirmed the diagnosis of infected subdural hematoma (ISH). Abscess culture results were positive for Escherichia coli. The patient's symptoms resolved postoperatively with subsequent antibiotic therapy. However, 4 months after the operation, he suddenly died of severe sepsis and disseminated intravascular coagulation following cholecystitis, which was possibly associated with splenectomy. The clinical presentation, diagnosis, and treatment of an unusual case of ISH have been discussed. We emphasize that DWI and enhanced MR imaging may be useful for diagnosing ISH, and serial DWI evaluations may help in monitoring the therapeutic response in ISH.

摘要

一名80岁男性,13年前因胃癌接受了全胃切除术和脾切除术,在一次交通事故1个月后出现头痛、嗜睡和高热。脑部CT扫描显示双侧硬膜下积液。弥散加权成像(DWI)显示左侧硬膜下积液内有高低混合信号强度,对比增强磁共振成像显示左侧硬膜下积液有包膜强化。该患者被诊断为左侧硬膜下积脓,钻了2个骨孔进行引流和冲洗。手术所见显示硬脑膜下有一层新膜。新膜内有陈旧性血肿和黄白色脓性液体。这证实了感染性硬膜下血肿(ISH)的诊断。脓肿培养结果显示大肠杆菌阳性。患者术后症状通过后续抗生素治疗得以缓解。然而,术后4个月,他在胆囊炎后突然死于严重脓毒症和弥散性血管内凝血,这可能与脾切除术有关。本文讨论了一例不寻常的ISH病例的临床表现、诊断和治疗。我们强调,DWI和增强磁共振成像可能有助于诊断ISH,连续的DWI评估可能有助于监测ISH的治疗反应。

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