Conradt Matthias, Dierk Jan-Michael, Schlumberger Pia, Albohn Christina, Rauh Elisabeth, Hinney Anke, Hebebrand Johannes, Rief Winfried
Psychology Department, Marburg University, Marburg, Germany.
J Psychosom Res. 2009 Apr;66(4):287-95. doi: 10.1016/j.jpsychores.2008.09.003. Epub 2008 Dec 17.
This study tested the effects of a consultation using genetic information about obesity on attitudes relating to weight loss goals, self-blame about eating, and weight-related coping in obese individuals. Furthermore, the study sought to explore possible predictors for weight gain/loss.
A total of 411 obese individuals were randomly assigned to two standardized consultations, with and without genetic information about obesity, and a control group without any intervention. After a 6-month follow-up, 253 obese individuals of the intervention groups and 98 individuals of the control group had a complete dataset. Data were analyzed regarding the independent variables assessment time, treatment group, and the familial predisposition (at least one obese parent or sibling). As dependent measures, attitudes about weight loss goals, weight-related self-blame, coping, and body shame were assessed via questionnaire or interview.
Individuals with and without a familial predisposition profited in different ways from a consultation using genetic information about obesity: at follow-up, individuals with a familial predisposition reported mainly a relieving effect (less self-blame about eating). Both groups reported an adjustment to more realistic weight loss goals and a greater satisfaction with a 5% weight loss. Furthermore, the more negative obese individuals felt about their current weight at baseline, the higher the risk that these individuals had gained weight at follow-up.
A consultation focusing on genetic factors might be helpful for obese individuals regardless of their familial predisposition, but only predisposed individuals showed a decrease in self-blame about eating. Negative thoughts and feelings about current weight might predict future weight gain.
本研究测试了利用肥胖相关基因信息进行的咨询对肥胖个体在减肥目标态度、饮食自责以及体重相关应对方式方面的影响。此外,该研究还试图探索体重增加/减轻的可能预测因素。
总共411名肥胖个体被随机分配到两种标准化咨询组,一组有肥胖相关基因信息,另一组没有,还有一个不进行任何干预的对照组。经过6个月的随访,干预组的253名肥胖个体和对照组的98名个体拥有完整的数据集。对自变量评估时间、治疗组和家族易感性(至少有一位肥胖的父母或兄弟姐妹)进行了数据分析。作为因变量,通过问卷调查或访谈评估了对减肥目标的态度、与体重相关的自责、应对方式和身体羞耻感。
有家族易感性和没有家族易感性的个体从利用肥胖相关基因信息进行的咨询中以不同方式获益:在随访时,有家族易感性的个体主要报告了一种缓解作用(饮食方面的自责减少)。两组都报告了对更现实减肥目标的调整以及对体重减轻5%的更大满意度。此外,肥胖个体在基线时对自己当前体重感觉越消极,这些个体在随访时体重增加的风险就越高。
关注基因因素的咨询可能对肥胖个体有帮助,无论其家族易感性如何,但只有有家族易感性的个体在饮食自责方面有所减少。对当前体重的消极想法和感受可能预测未来体重增加。