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肥胖症的基因检测:意义与挑战。

Genetic Testing for Obesity: Implications and Challenges.

机构信息

Research Center for Health Care Decision-making, Inc., 706 East Hartwell Lane, Wyndmoor, PA, 19038, USA.

出版信息

Curr Obes Rep. 2017 Mar;6(1):93-100. doi: 10.1007/s13679-017-0245-z.

DOI:10.1007/s13679-017-0245-z
PMID:28233281
Abstract

PURPOSE OF REVIEW

This review summarizes the experimental literature on behavioral outcomes and psychological effects of genetic testing for obesity. Such tests, although of dubious value, are increasingly marketed to the public, and there has been concern that while results may encourage some consumers to increase the healthfulness of their lifestyles, others may interpret feedback in maladaptive ways.

RECENT FINDINGS

Hypothetical vignettes have been used in artificial settings; few studies have investigated outcomes of actual test results. At present, the effects of genetic testing for obesity seem limited to improving consumers' weight control intentions and motivation rather than actual dietary behavior. Evidence for negative psychological consequences is scarce and seems of greater concern for normal weight persons than for those who are overweight. Better research designs carried out in the field rather than the laboratory with more diverse samples are needed.

摘要

目的综述

本文总结了肥胖基因检测的行为结果和心理影响的实验文献。尽管这些检测的价值值得怀疑,但它们仍越来越多地推向公众市场,人们担心的是,尽管检测结果可能会鼓励一些消费者提高生活方式的健康度,但其他人可能会以不适应的方式来解释反馈。

最新发现

在人为环境中使用了假设的情景;很少有研究调查实际检测结果的结果。目前,肥胖基因检测的效果似乎仅限于改善消费者的体重控制意图和动机,而不是实际的饮食行为。关于负面心理后果的证据很少,而且对于正常体重的人来说,似乎比超重的人更令人担忧。需要在实验室以外的领域进行更好的研究设计,采用更多样化的样本。

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Obesity Characteristics Are Poor Predictors of Genetic Mutations Associated with Obesity.肥胖特征并非与肥胖相关基因突变的良好预测指标。
J Clin Med. 2023 Oct 7;12(19):6396. doi: 10.3390/jcm12196396.
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An experiment assessing effects of personalized feedback about genetic susceptibility to obesity on attitudes towards diet and exercise.一项评估关于肥胖遗传易感性的个性化反馈对饮食和运动态度影响的实验。

本文引用的文献

1
Marginally scientific? Genetic testing of children and adolescents for lifestyle and health promotion.科学性存疑?对儿童和青少年进行生活方式及健康促进方面的基因检测。
J Law Biosci. 2015 Nov 16;2(3):627-644. doi: 10.1093/jlb/lsv038. eCollection 2015 Nov.
2
FTO genotype and weight loss in diet and lifestyle interventions: a systematic review and meta-analysis.FTO基因分型与饮食及生活方式干预中的体重减轻:一项系统评价与荟萃分析。
Am J Clin Nutr. 2016 Apr;103(4):1162-70. doi: 10.3945/ajcn.115.123448. Epub 2016 Feb 17.
3
Genetic causal beliefs about obesity, self-efficacy for weight control, and obesity-related behaviours in a middle-aged female cohort.
Appetite. 2018 Jan 1;120:23-31. doi: 10.1016/j.appet.2017.08.021. Epub 2017 Aug 31.
中年女性队列中关于肥胖的遗传因果信念、体重控制自我效能感及肥胖相关行为
Psychol Health. 2016;31(4):420-35. doi: 10.1080/08870446.2015.1115503. Epub 2016 Jan 2.
4
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans.人类中的FTO肥胖变体通路与脂肪细胞褐变
N Engl J Med. 2015 Sep 3;373(10):895-907. doi: 10.1056/NEJMoa1502214. Epub 2015 Aug 19.
5
Genetic susceptibility testing and readiness to control weight: Results from a randomized controlled trial.遗传易感性检测与体重控制准备度:一项随机对照试验的结果。
Obesity (Silver Spring). 2015 Feb;23(2):305-12. doi: 10.1002/oby.20958. Epub 2014 Dec 17.
6
Variability in children's eating response to portion size. A biobehavioral perspective.儿童饮食对食物分量反应的变异性:一种生物行为学视角
Appetite. 2015 May;88:5-10. doi: 10.1016/j.appet.2014.10.001. Epub 2014 Oct 8.
7
A randomized trial of the clinical utility of genetic testing for obesity: design and implementation considerations.肥胖基因检测临床效用的随机试验:设计与实施考量
Clin Trials. 2014 Feb;11(1):102-13. doi: 10.1177/1740774513508029. Epub 2013 Nov 11.
8
Why does genetic causal information alter perceived treatment effectiveness? An analogue study.为什么遗传因果信息会改变人们对治疗效果的看法?一项模拟研究。
Br J Health Psychol. 2012 May;17(2):294-313. doi: 10.1111/j.2044-8287.2011.02038.x. Epub 2011 Jul 6.
9
Psychological responses to genetic testing for weight gain: a vignette study.体重增加基因检测的心理反应:案例研究。
Obesity (Silver Spring). 2012 Mar;20(3):540-6. doi: 10.1038/oby.2011.324. Epub 2011 Oct 27.
10
Genetic essentialism: on the deceptive determinism of DNA.遗传本质论:论 DNA 的欺骗性决定论。
Psychol Bull. 2011 Sep;137(5):800-18. doi: 10.1037/a0021860.