Djasim Urville M, Wolvius Eppo B, Bos Joop A, van Neck Han W, van der Wal Karel G
Research Fellow, Department of Oral and Maxillofacial Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
J Oral Maxillofac Surg. 2009 Apr;67(4):818-26. doi: 10.1016/j.joms.2008.08.016.
To investigate continuous distraction osteogenesis (DO) of the nasal bones in a rabbit model, and to compare data from this continuous DO study with data from a previously conducted discontinuous DO study. In addition, radiographic and ultrasonographic bone-fill scores were determined to investigate whether these scores provided reliable predictive value for the amount of new bone formation in the distraction area.
Skeletally mature female New Zealand White rabbits were subjected to distraction of the nasal bones. A custom-made continuous distractor was used to perform automatic non-stop distraction. Bone data were obtained from radiography, ultrasonography, and microcomputed tomography. Data from this experiment were compared with data from a previous study on discontinuous distraction rhythms.
Ultrasonographic bone-fill scores correlated significantly to actual bone volume in contrast to radiographic bone-fill scores. Bone volume was significantly higher in the continuous DO group compared with the discontinuous DO groups.
Continuous distraction resulted in accelerated osteogenesis compared with discontinuous distraction. Furthermore, bone-fill scores based on ultrasonography showed a significant correlation with actual bone volumes.
在兔模型中研究鼻骨的连续牵引成骨（DO），并将该连续DO研究的数据与先前进行的间断DO研究的数据进行比较。此外，确定放射学和超声骨填充评分，以研究这些评分是否能为牵引区域新骨形成量提供可靠的预测价值。
对骨骼成熟的雌性新西兰白兔进行鼻骨牵引。使用定制的连续牵引器进行自动不间断牵引。通过放射学、超声和微型计算机断层扫描获取骨数据。将本实验的数据与先前关于间断牵引节律的研究数据进行比较。
与放射学骨填充评分相比，超声骨填充评分与实际骨体积显著相关。连续DO组的骨体积显著高于间断DO组。
与间断牵引相比，连续牵引导致成骨加速。此外，基于超声的骨填充评分与实际骨体积显著相关。
