[瞬时受体电位亚家族mRNA在大鼠睾丸中的表达]
[Expression of transient receptor potential subfamily mRNAs in rat testes].
作者信息
Xu Zhan-Ping, Gao Wei-Cheng, Wang Huai-Peng, Wang Xing-Huan
机构信息
Department of Urology, Guangdong Provincial People's Hospital, Guangzhou, China.
出版信息
Nan Fang Yi Ke Da Xue Xue Bao. 2009 Mar;29(3):519-20.
OBJECTIVE
To study the expression of the mRNAs of transient receptor potential (TRP) gene subfamily TRPV and TRPM in rat testes.
METHODS
Normal SD rat testes were collected and the expression of TRPV and TRPM mRNAs were detected by routine RT-PCR.
RESULTS
The TRPV4, TRPV5, TRPV6, TRPM3, TRPM4 and TRPM8 mRNAs were detected in the rat testes, but the other members of TRPV and TRPM family were not detected.
CONCLUSIONS
TRPV4, TRPV5, TRPV6, TRPM3, TRPM4 and TRPM8 are expressed in rat testes. This finding provides the basis for exploring the functions of TRPV and TRPM in the testes and the relation between testis diseases and the TRP family.
目的
研究瞬时受体电位（TRP）基因亚家族TRPV和TRPM的mRNA在大鼠睾丸中的表达情况。
方法
收集正常SD大鼠的睾丸，采用常规逆转录聚合酶链反应（RT-PCR）检测TRPV和TRPM mRNA的表达。
结果
在大鼠睾丸中检测到TRPV4、TRPV5、TRPV6、TRPM3、TRPM4和TRPM8的mRNA，但未检测到TRPV和TRPM家族的其他成员。
结论
TRPV4、TRPV5、TRPV6、TRPM3、TRPM4和TRPM8在大鼠睾丸中表达。这一发现为探索TRPV和TRPM在睾丸中的功能以及睾丸疾病与TRP家族之间的关系提供了依据。
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