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Synaptic transmission block by presynaptic injection of oligomeric amyloid beta.
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A conserved clathrin assembly motif essential for synaptic vesicle endocytosis.
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Clathrin and synaptic vesicle endocytosis: studies at the squid giant synapse.
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The effect of amyloid-β peptide on synaptic plasticity and memory is influenced by different isoforms, concentrations, and aggregation status.
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Amyloid-β and Synaptic Vesicle Dynamics: A Cacophonic Orchestra.
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Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles.
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Identification of human pregnane X receptor antagonists utilizing a high-throughput screening platform.
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The duality of amyloid-β: its role in normal and Alzheimer's disease states.
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Amyloid β-based therapy for Alzheimer's disease: challenges, successes and future.
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Cyclic Glycine-Proline Improves Memory and Reduces Amyloid Plaque Load in APP/PS1 Transgenic Mouse Model of Alzheimer's Disease.
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Physiological Roles of β-amyloid in Regulating Synaptic Function: Implications for AD Pathophysiology.
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Relationship Between Amyloid-β Deposition and Blood-Brain Barrier Dysfunction in Alzheimer's Disease.
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Selection of mutant µplasmin for amyloid-β cleavage in vivo.
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Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta.
Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5907-12. doi: 10.1073/pnas.0901229106. Epub 2009 Mar 24.
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Distinct pools of beta-amyloid in Alzheimer disease-affected brain: a clinicopathologic study.
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GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice.
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Intracellular amyloid-beta in Alzheimer's disease.
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Signal transduction cascades associated with oxidative stress in Alzheimer's disease.
J Alzheimers Dis. 2007 May;11(2):143-52. doi: 10.3233/jad-2007-11202.
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Abeta, tau and ApoE4 in Alzheimer's disease: the axonal connection.
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Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system.
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Apoptosis is secondary to non-apoptotic axonal degeneration in neurons exposed to Abeta in distal axons.
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