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曲霉菌属对肺泡毛细血管屏障的侵袭：对免疫功能低下的侵袭性肺曲霉病患者的治疗和诊断意义。

Invasion of the alveolar-capillary barrier by Aspergillus spp.: therapeutic and diagnostic implications for immunocompromised patients with invasive pulmonary aspergillosis.

作者信息

Hope William W

机构信息

The University of Manchester, Manchester, UK.

出版信息

Med Mycol. 2009;47 Suppl 1:S291-8. doi: 10.1080/13693780802510232. Epub 2009 Mar 21.

DOI:10.1080/13693780802510232
PMID:19306226
Abstract

Aspergillus spp. are leading causes of morbidity and mortality in immunocompromised patients. This review provides an overview of host defenses, the mechanisms by which the alveolar-capillary barrier is breeched by Aspergillus, and the implications for diagnosis and treatment of patients with invasive pulmonary aspergillosis.

摘要

曲霉属真菌是免疫功能低下患者发病和死亡的主要原因。本综述概述了宿主防御机制、曲霉突破肺泡 - 毛细血管屏障的机制，以及对侵袭性肺曲霉病患者诊断和治疗的意义。

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