Flood Karen M, Said Soha, Geary Michael, Robson Michael, Fitzpatrick Christopher, Malone Fergal D
Department of Obstetrics and Gynaecology, Rotunda Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland.
Am J Obstet Gynecol. 2009 Jun;200(6):632.e1-6. doi: 10.1016/j.ajog.2009.02.001.
The purpose of this study was to identify changing trends in peripartum hysterectomy (PH) in a single large obstetric population over the last 40 years.
A retrospective cohort study was performed from 1966-2005 of patients who had PH in any of the 3 Dublin obstetric hospitals. Cases were identified, and details were obtained from the combined patient databases of each hospital.
There were 872,379 deliveries during the study period, among which 358 women underwent PH (0.4/1000 deliveries). In a comparison of the study decades 1966-1975 with 1996-2005, PH decreased from 0.9 per 1000 deliveries to 0.2 of 1000 deliveries. Although the overall cesarean delivery rate has increased from 6-19% during these 2 decades, the percentage of PH that occurs in the setting of a previous cesarean delivery has increased from 27-57% (P < .00001). Indications for PH have changed significantly in this time period, with "uterine rupture" as the indication for PH decreasing from 40.5-9.3% (P < .0001) and placenta accreta as the indication increasing significantly from 5.4-46.5% (P < .00001).
PH has decreased over the last 4 decades. However, alongside the rising cesarean delivery rate, there has been a marked increase in the incidence of placenta accreta.
本研究旨在确定过去40年中单一大型产科人群围产期子宫切除术(PH)的变化趋势。
对1966年至2005年期间在都柏林3家产科医院中接受过PH的患者进行回顾性队列研究。确定病例,并从每家医院的综合患者数据库中获取详细信息。
研究期间共分娩872,379例,其中358名妇女接受了PH(每1000例分娩中有0.4例)。在比较1966 - 1975年与1996 - 2005年这两个研究十年时,PH从每1000例分娩中的0.9例降至每1000例分娩中的0.2例。尽管这20年中总体剖宫产率从6%升至19%,但既往剖宫产情况下发生PH的百分比从27%升至57%(P <.00001)。在此期间,PH的指征发生了显著变化,“子宫破裂”作为PH的指征从40.5%降至9.3%(P <.0001),而胎盘植入作为指征则从5.4%显著升至46.5%(P <.00001)。
在过去40年中PH有所下降。然而,随着剖宫产率的上升,胎盘植入的发生率显著增加。