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土耳其一家三级中心的 7 年回顾性研究:紧急围产期子宫切除术的适应证、风险因素和结局。

Indications, risk factors, and outcomes of emergency peripartum hysterectomy: A 7-year retrospective study at a tertiary center in Turkey.

机构信息

Department of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital, Turkey.

Department of Obstetrics and Gynecology, Izmir Tinaztepe University Faculty of Medicine, Turkey.

出版信息

Malawi Med J. 2023 Mar;35(1):31-42. doi: 10.4314/mmj.v35i1.7.

Abstract

OBJECTIVE

To determine the incidence, indications, the risk factors, complications, maternal morbidity and mortality of emergency peripartum hysterectomy (EPH), and perinatal outcomes at a tertiary hospital, Turkey.

METHODS

We analyzed 71 cases of EPH from 2012 to 2019 at a tertiary hospital in a retrospective study. There were 142 control patients.

RESULTS

There were 71 EPH out of 69,504 deliveries, for an overall incidence of 1.02 per 1000 births. The main indication for peripartum hysterectomy was abnormal placentation (67.6%), followed by uterine atony (28.1%), and uterine rupture (4.2%). Cesarean section (CS) and previous CS are major risk indicators for EPH. Other risk indicators are advanced maternal age (≥ 35 years) and multiparity. All patients with abnormal placentation had a previous CS. 93% of EPH were performed during and/or after CS, and 7% after vaginal delivery. 69% of EPH were made in total and 31% were subtotal. The three most common maternal morbidity included: wound infection and febrile morbidity (26.7%), bladder injury (16.9%), and disseminated intravascular coagulopathy (11.2%). There were no maternal deaths but perinatal mortality was 4%.

CONCLUSION

The most common indication for EPH was abnormal placentation. Also, CS and previous CS are major risk factors of EPH. Other risk factors for EPH are advanced maternal age (≥ 35 years) and multiparity. Moreover, all unnecessary CS should be avoided.

摘要

目的

在土耳其的一家三级医院,确定紧急围产期子宫切除术(EPH)的发生率、指征、危险因素、并发症、产妇发病率和死亡率,以及围产儿结局。

方法

我们在一项回顾性研究中分析了 2012 年至 2019 年在一家三级医院发生的 71 例 EPH 病例。有 142 例对照患者。

结果

在 69504 例分娩中,有 71 例发生 EPH,总体发生率为每 1000 例分娩 1.02 例。围产期子宫切除术的主要指征是异常胎盘(67.6%),其次是子宫收缩乏力(28.1%)和子宫破裂(4.2%)。剖宫产术(CS)和既往 CS 是 EPH 的主要危险因素。其他危险因素是高龄产妇(≥35 岁)和多胎妊娠。所有异常胎盘的患者均有既往 CS。93%的 EPH 在 CS 期间和/或之后进行,7%在阴道分娩后进行。69%的 EPH 是全子宫切除术,31%是次全子宫切除术。产妇发病率最常见的三种包括:伤口感染和发热发病率(26.7%)、膀胱损伤(16.9%)和弥散性血管内凝血(11.2%)。没有产妇死亡,但围产儿死亡率为 4%。

结论

EPH 最常见的指征是异常胎盘。此外,CS 和既往 CS 是 EPH 的主要危险因素。EPH 的其他危险因素是高龄产妇(≥35 岁)和多胎妊娠。此外,应避免所有不必要的 CS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4657/10645903/2d4575f40feb/MMJ3501-0031Fig1.jpg

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