Brown V J, Bowman E M, Robbins T W
Laboratory of Sensorimotor Research, National Eye Institute Bethesda, Maryland 20892.
Behav Neurosci. 1991 Aug;105(4):567-78. doi: 10.1037//0735-7044.105.4.567.
Rats with lesions of the medial agranular frontal cortex (AGm) were tested for sensorimotor function. Spatial response bias and reaction time to lateralized visual targets were recorded in an automated test of visual reaction time. The same rats were also tested for somatosensory capacity and on a skilled reaching task. In all tasks, there was an ipsilateral response bias but no evidence of sensory neglect. In the visual reaction time task, initiation time was lengthened bilaterally. These deficits may parallel the effects on motor function after unilateral frontal cortical lesioning in primates. The results support the hypothesis that rat AGm contains a homologue of primate secondary motor cortex.
对内侧无颗粒额叶皮质（AGm）受损的大鼠进行感觉运动功能测试。在视觉反应时间的自动化测试中记录对侧化视觉目标的空间反应偏差和反应时间。对同一只大鼠还进行了体感能力测试和熟练抓握任务测试。在所有任务中，均存在同侧反应偏差，但没有感觉忽视的证据。在视觉反应时间任务中，双侧启动时间延长。这些缺陷可能与灵长类动物单侧额叶皮质损伤后对运动功能的影响相似。结果支持了大鼠AGm包含灵长类动物次级运动皮质同源物的假说。
