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子痫前期后的认知功能:一项探索性研究。

Cognitive function after pre-eclampsia: an explorative study.

作者信息

Baecke Martina, Spaanderman Mark E A, van der Werf Sieberen P

机构信息

Department of Clinical Psychology, Medical Centre Spectrum, Enschede, The Netherlands.

出版信息

J Psychosom Obstet Gynaecol. 2009 Mar;30(1):58-64. doi: 10.1080/01674820802546212.

DOI:10.1080/01674820802546212
PMID:19308784
Abstract

BACKGROUND

Pre-eclampsia and eclampsia relate to cerebral damage. Memory and concentration problems are frequently reported after these pregnancy-related vascular complications. We tested the hypothesis that in formerly pre-eclamptic women cognitive functioning is impaired as compared with healthy parous controls.

METHODS

Women with a recent history of pre-term pre-eclampsia (PPE; n = 47), term pre-eclampsia (TPE; N = 18), pre-term birth (PBI; n = 32) or an uneventful pregnancy (UPR; n = 72) completed a set of questionnaires, measuring cognitive problems, PTSD, depression, anxiety and fatigue. In addition, in PPE and UPR participants we tested neuropsychological performance.

RESULTS

PBI is related to higher levels of post-traumatic distress symptoms, which in turn diminished the neuropsychological test performance of PPE women. Nonetheless, women in the PPE and TPE groups did not report more cognitive problems than women in the PBI and UPR groups, but PPE raised the need for psychosocial cared.

CONCLUSIONS

Cognitive complaints are common amongst young mothers. When tested, only those with psychological co-morbidity have neuropsychological impairment.

摘要

背景

子痫前期和子痫与脑损伤有关。在这些与妊娠相关的血管并发症之后,经常会报告记忆和注意力问题。我们检验了这样一个假设,即与健康经产妇对照组相比,既往患子痫前期的女性认知功能受损。

方法

近期有早产子痫前期(PPE;n = 47)、足月子痫前期(TPE;N = 18)、早产(PBI;n = 32)或正常妊娠(UPR;n = 72)病史的女性完成了一组问卷,测量认知问题、创伤后应激障碍(PTSD)、抑郁、焦虑和疲劳。此外,在PPE和UPR参与者中,我们测试了神经心理学表现。

结果

PBI与更高水平的创伤后应激症状相关,这反过来又降低了PPE女性的神经心理学测试表现。尽管如此,PPE组和TPE组的女性报告的认知问题并不比PBI组和UPR组的女性多,但PPE增加了对心理社会护理的需求。

结论

认知主诉在年轻母亲中很常见。经测试,只有那些伴有心理共病的人才有神经心理学损伤。

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