细胞与细胞外基质相互作用中的跨膜分子组装体

Transmembrane molecular assemblies in cell-extracellular matrix interactions.

作者信息

Turner C E, Burridge K

机构信息

SUNY Health Science Center, Syracuse.

出版信息

Curr Opin Cell Biol. 1991 Oct;3(5):849-53. doi: 10.1016/0955-0674(91)90059-8.

DOI:10.1016/0955-0674(91)90059-8

PMID:1931085

Abstract

Several new interactions have been identified and proteins characterized in focal adhesions. Together they suggest alternative or parallel linkages between actin filaments and members of the integrin family of extracellular receptors. Transformed cells continue to serve as models for studying the assembly and disassembly of these adhesions.

摘要

已经确定了几种新的相互作用，并对粘着斑中的蛋白质进行了表征。它们共同表明肌动蛋白丝与细胞外受体整合素家族成员之间存在替代或平行的联系。转化细胞继续作为研究这些粘着斑组装和拆卸的模型。