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利用铟-111标记的人多克隆免疫球蛋白检测局灶性感染

Detection of focal infection by 111In-human polyclonal IgG.

作者信息

Tumeh S S, Carvalho P A, van den Abbeele A D, Maguire J H, Rauh D A, Neptune M, Kassis A I

机构信息

Department of Radiology, Brigham & Women's Hospital, Boston, Massachusetts 02115.

出版信息

J Nucl Biol Med (1991). 1991 Jan-Mar;35(1):4-9.

PMID:1932174
Abstract

Eleven patients with suspected foci of inflammation and/or infection were scanned with 111In-labeled polyclonal human IgG. Seven patients were suspected of having the source of their infection in the abdomen, three in the musculoskeletal system and one in the thoracic aorta. The test was truly positive in seven patients, truly negative in three and falsely negative in one. All the true positive cases showed abnormally increased radiopharmaceutical uptake at the site of infection by six hours, suggesting the diagnosis, although the intensity of uptake increased progressively 24 hours later. There were no untoward effects noted in this series. This examination is potentially useful in the early depiction of focal sources of infection/inflammation.

摘要

11例怀疑有炎症和/或感染病灶的患者用111In标记的多克隆人IgG进行扫描。7例患者怀疑感染源在腹部,3例在肌肉骨骼系统,1例在胸主动脉。该检查在7例患者中结果为真阳性,3例为真阴性,1例为假阴性。所有真阳性病例在6小时时感染部位的放射性药物摄取异常增加,提示诊断,尽管摄取强度在24小时后逐渐增加。本系列中未观察到不良影响。这项检查在早期描绘感染/炎症的局灶性来源方面可能有用。

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Detection of focal infection by 111In-human polyclonal IgG.利用铟-111标记的人多克隆免疫球蛋白检测局灶性感染
J Nucl Biol Med (1991). 1991 Jan-Mar;35(1):4-9.
2
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