Demir Omer, Demir Tevfik, Kefi Aykut, Secil Mustafa, Comlekci Abdurrahman, Yesil Sena, Esen Ahmet Adil
Department of Urology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
Urol Int. 2009;82(2):175-8. doi: 10.1159/000200795. Epub 2009 Mar 19.
The constellation of truncal obesity, glucose intolerance, dyslipidemia (high triglycerides, low HDL cholesterol), and hypertension has been recognized as metabolic syndrome. However, the pathophysiological association between metabolic syndrome and erectile dysfunction (ED) has not yet been clearly determined. This study aimed to evaluate the penile Doppler ultrasound (PDU) findings of ED patients with metabolic syndrome.
Sixty-one age-matched ED patients with or without metabolic syndrome were included in the study. Patients were investigated by grouping according to risk factors of metabolic syndrome with PDU parameters (5th, 10th and 20th minute peak systolic velocity and end-diastolic velocity). PDU parameters of patients with and without metabolic syndrome were compared.
The mean age of the patients were 54.9 +/- 8.3 and 54.9 +/- 7.6 years for the groups of with (n = 27) and without (n = 34) metabolic syndrome, respectively. When the mean peak flow velocities were compared with presence of metabolic syndrome, we observed differences between at the 5th, 10th and 20th minute peak systolic velocities (p = 0.083, p = 0.022 and p = 0.080, respectively).
Metabolic syndrome seems to be the potential risk factor for ED, which may exert its effect by decreased arterial inflow due to endothelial dysfunction.
躯干肥胖、糖耐量异常、血脂异常（高甘油三酯、低高密度脂蛋白胆固醇）和高血压的组合已被确认为代谢综合征。然而，代谢综合征与勃起功能障碍（ED）之间的病理生理关联尚未明确确定。本研究旨在评估患有代谢综合征的ED患者的阴茎多普勒超声（PDU）检查结果。
本研究纳入了61例年龄匹配的有或无代谢综合征的ED患者。根据代谢综合征的危险因素对患者进行分组，并使用PDU参数（第5、10和20分钟的收缩期峰值流速和舒张末期流速）进行研究。比较了有和无代谢综合征患者的PDU参数。
有代谢综合征组（n = 27）和无代谢综合征组（n = 34）患者的平均年龄分别为54.9 +/- 8.3岁和54.9 +/- 7.6岁。当比较平均峰值流速与代谢综合征的存在情况时，我们观察到在第5、10和20分钟的收缩期峰值流速之间存在差异（分别为p = 0.083、p = 0.022和p = 0.080）。
代谢综合征似乎是ED的潜在危险因素，它可能通过内皮功能障碍导致动脉血流减少而发挥作用。
