Soga Hideo, Takenaka Atsushi, Ooba Takeshi, Nakano Yuzo, Miyake Hideaki, Takeda Masashi, Tanaka Kazushi, Hara Isao, Fujisawa Masato
Department of Organ Therapeutics, Division of Urology, Kobe University Graduate School of Medicine, Kobe, Japan.
Urol Int. 2009;82(2):222-6. doi: 10.1159/000200804. Epub 2009 Mar 19.
We retrospectively analyzed 6 cases of adrenal cortical carcinoma (ACC) treated during a 12-year period at a single institution.
We reviewed the clinical and pathological records and updated the follow-up of the patients treated and observed in our institution between 1995 and 2006.
All 6 patients underwent surgery for ACC. The mean age at diagnosis was 53.3 years (range 36-72). The median follow-up was 50.7 months (range 13-132). Three patients were clinically classified as stage II, 2 as stage III and 1 as stage IV with bone metastasis. The 5-year overall survival was 62.5%. Recurrences or metastases occurred in 4 patients. Two patients without reoperation for metastases died, and others with radical treatments such as surgery, chemotherapy, transcatheter arterial embolization and/or radiation remain alive.
In our experience, transcatheter arterial embolization was effective against liver metastasis.
我们回顾性分析了在一家机构12年期间治疗的6例肾上腺皮质癌（ACC）患者。
我们回顾了临床和病理记录，并更新了1995年至2006年在我们机构接受治疗和观察的患者的随访情况。
所有6例患者均接受了ACC手术。诊断时的平均年龄为53.3岁（范围36 - 72岁）。中位随访时间为50.7个月（范围13 - 132个月）。3例患者临床分类为II期，2例为III期，1例为IV期伴骨转移。5年总生存率为62.5%。4例患者出现复发或转移。2例未因转移再次手术的患者死亡，其他接受手术、化疗、经导管动脉栓塞和/或放疗等根治性治疗的患者仍存活。
根据我们的经验，经导管动脉栓塞对肝转移有效。
