一家机构12年肾上腺皮质癌治疗经验：手术治疗及经导管动脉栓塞后的长期生存情况

A twelve-year experience with adrenal cortical carcinoma in a single institution: long-term survival after surgical treatment and transcatheter arterial embolization.

作者信息

Soga Hideo, Takenaka Atsushi, Ooba Takeshi, Nakano Yuzo, Miyake Hideaki, Takeda Masashi, Tanaka Kazushi, Hara Isao, Fujisawa Masato

机构信息

Department of Organ Therapeutics, Division of Urology, Kobe University Graduate School of Medicine, Kobe, Japan.

出版信息

Urol Int. 2009;82(2):222-6. doi: 10.1159/000200804. Epub 2009 Mar 19.

DOI:10.1159/000200804

PMID:19322014

Abstract

INTRODUCTION

We retrospectively analyzed 6 cases of adrenal cortical carcinoma (ACC) treated during a 12-year period at a single institution.

PATIENTS AND METHODS

We reviewed the clinical and pathological records and updated the follow-up of the patients treated and observed in our institution between 1995 and 2006.

RESULTS

All 6 patients underwent surgery for ACC. The mean age at diagnosis was 53.3 years (range 36-72). The median follow-up was 50.7 months (range 13-132). Three patients were clinically classified as stage II, 2 as stage III and 1 as stage IV with bone metastasis. The 5-year overall survival was 62.5%. Recurrences or metastases occurred in 4 patients. Two patients without reoperation for metastases died, and others with radical treatments such as surgery, chemotherapy, transcatheter arterial embolization and/or radiation remain alive.

CONCLUSIONS

In our experience, transcatheter arterial embolization was effective against liver metastasis.

摘要

引言

我们回顾性分析了在一家机构12年期间治疗的6例肾上腺皮质癌（ACC）患者。

患者与方法

我们回顾了临床和病理记录，并更新了1995年至2006年在我们机构接受治疗和观察的患者的随访情况。

结果

所有6例患者均接受了ACC手术。诊断时的平均年龄为53.3岁（范围36 - 72岁）。中位随访时间为50.7个月（范围13 - 132个月）。3例患者临床分类为II期，2例为III期，1例为IV期伴骨转移。5年总生存率为62.5%。4例患者出现复发或转移。2例未因转移再次手术的患者死亡，其他接受手术、化疗、经导管动脉栓塞和/或放疗等根治性治疗的患者仍存活。