Department of Transplantation and Surgery, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Department of Endocrinology and Department of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Front Endocrinol (Lausanne). 2021 Apr 30;12:677187. doi: 10.3389/fendo.2021.677187. eCollection 2021.
There is very limited experience regarding the interventional radiological treatment of adrenocortical cancer (ACC). We present the case of a 57-year-old female patient with a large, potentially unresectable left-sided ACC and two hepatic metastases. Both liver tumors were effectively treated by trans-arterial embolization (TAE), followed by TAE of the bulky primary tumor as a life-saving intervention necessitated by severe intratumoral bleeding. Surgical removal of the primary tumor revealed complete necrosis. The patient is considered tumor free after 3.5 years. To the best of our knowledge, this is the first report to show that even a primary ACC may be completely ablated by selective embolization, and the fourth to prove the curative potential of liver TAE for ACC metastases. This case highlights the potential of selective embolization in ACC treatment.
关于肾上腺皮质癌（ACC）的介入放射治疗经验非常有限。我们报告了一例 57 岁女性患者，其左侧有一个大的、可能无法切除的 ACC 和两个肝转移灶。两个肝肿瘤均通过经动脉栓塞术（TAE）有效治疗，随后对体积较大的原发性肿瘤进行 TAE，这是由于严重的肿瘤内出血而进行的挽救生命的干预措施。手术切除原发性肿瘤显示完全坏死。患者在 3.5 年后被认为无肿瘤。据我们所知，这是第一个表明即使是原发性 ACC 也可以通过选择性栓塞完全消融的报告，也是第四个证明肝 TAE 治疗 ACC 转移灶的疗效的报告。该病例强调了选择性栓塞在 ACC 治疗中的潜力。
