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构建复杂组织:毛发工程所需分子的高通量筛选

Building complex tissues: high-throughput screening for molecules required in hair engineering.

作者信息

Lee Lily F, Chuong Cheng-Ming

机构信息

Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

出版信息

J Invest Dermatol. 2009 Apr;129(4):815-7. doi: 10.1038/jid.2008.434.

Abstract

A fully functional model of hair reconstitution remains elusive because of the complexity of cellular organization and the number of molecular interactions that must be approximated. In this issue, Havlickova et al. (2009) report a significant contribution to hair engineering with their human folliculoid microsphere assay.

摘要

由于细胞组织的复杂性以及必须近似模拟的分子相互作用的数量,头发重建的全功能模型仍然难以实现。在本期中,哈夫利科娃等人(2009年)通过其人类毛囊样微球试验报告了对毛发工程的重大贡献。

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本文引用的文献

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A human folliculoid microsphere assay for exploring epithelial- mesenchymal interactions in the human hair follicle.
J Invest Dermatol. 2009 Apr;129(4):972-83. doi: 10.1038/jid.2008.315. Epub 2008 Oct 16.
2
3
Hair follicle regeneration using grafted rodent and human cells.利用移植的啮齿动物和人类细胞进行毛囊再生。
J Invest Dermatol. 2007 Sep;127(9):2106-15. doi: 10.1038/sj.jid.5700823. Epub 2007 Apr 12.
8
Capturing and profiling adult hair follicle stem cells.捕获并分析成人毛囊干细胞。
Nat Biotechnol. 2004 Apr;22(4):411-7. doi: 10.1038/nbt950. Epub 2004 Mar 14.
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Cultured human hair follicles and growth factors.
J Invest Dermatol. 1995 May;104(5 Suppl):44S-45S. doi: 10.1038/jid.1995.61.

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