Kristensen Ida Bruun, Møller Hanne, Kjaerskov Mette Wanscher, Yderstraede Knud, Møller Michael Boe, Bergmann Olav J
Department of Haematology, Odense University Hospital, Odense C, Denmark.
Acta Derm Venereol. 2009;89(2):175-7. doi: 10.2340/00015555-0590.
We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gangrenosum, and it underlines the importance of performing re-biopsy of non-healing ulcers, especially in patients with an underlying haematological disease.
我们在此报告一例骨髓增生异常综合征患者发生坏疽性脓皮病，进而发展为髓系肉瘤，这是向急性白血病转化的迹象。该患者通过强化化疗成功治愈并实现完全缓解，原本不断扩大的溃疡开始愈合。这是首例报告的坏疽性脓皮病继发母细胞浸润病例，它强调了对不愈合溃疡进行再次活检的重要性，尤其是对于患有潜在血液系统疾病的患者。
