Saito M, Kondo A, Kato K, Gotoh M
Department of Urology, Nagoya University School of Medicine, Japan.
Br J Urol. 1991 Oct;68(4):365-8. doi: 10.1111/j.1464-410x.1991.tb15351.x.
Bladder dysfunction is a major complication of human T-lymphotrophic virus type I associated myelopathy (HAM). Four patients (3 females and 1 male, aged between 23 and 44 years), who had suffered from HAM for an average of 6 years complained variously of difficulty in micturition, frequency, bed wetting and/or urge incontinence. They were investigated urodynamically. A significant amount of urine was retained in the bladder of 3 patients. During the storage phase, bladder sensation was well preserved in all 4 patients but severe uninhibited detrusor contractions were observed in 3. At micturition, detrusor contractility was present in 3 and completely lost in 1. Of the 4 patients with HAM, 3 suffered from detrusor hyper-reflexia and 1 from detrusor areflexia.
膀胱功能障碍是I型人类嗜T淋巴细胞病毒相关脊髓病（HAM）的主要并发症。4例患者（3例女性，1例男性，年龄在23至44岁之间），平均患HAM 6年，分别诉说有排尿困难、尿频、尿床和/或急迫性尿失禁等症状。对他们进行了尿动力学检查。3例患者膀胱内潴留大量尿液。在储尿期，所有4例患者膀胱感觉均保存良好，但3例观察到严重的逼尿肌无抑制性收缩。排尿时，3例患者有逼尿肌收缩力，1例完全丧失。4例HAM患者中，3例患有逼尿肌反射亢进，1例患有逼尿肌无反射。
