托斯卡纳病毒的遗传多样性
Genetic diversity of Toscana virus.
作者信息
Collao Ximena, Palacios Gustavo, Sanbonmatsu-Gámez Sara, Pérez-Ruiz Mercedes, Negredo Ana I, Navarro-Marí José María, Grandadam Marc, Aransay Ana Maria, Lipkin W Ian, Tenorio Antonio, Sánchez-Seco María Paz
机构信息
Institute of Health "Carlos III," Madrid, Spain.
出版信息
Emerg Infect Dis. 2009 Apr;15(4):574-7. doi: 10.3201/eid1504.081111.
Distribution of Toscana virus (TOSV) is evolving with climate change, and pathogenicity may be higher in nonexposed populations outside areas of current prevalence (Mediterranean Basin). To characterize genetic diversity of TOSV, we determined the coding sequences of isolates from Spain and France. TOSV is more diverse than other well-studied phleboviruses (e.g.,Rift Valley fever virus).
托斯卡纳病毒（TOSV）的分布正随着气候变化而演变，在当前流行地区（地中海盆地）以外未接触过该病毒的人群中，其致病性可能更高。为了描述TOSV的遗传多样性，我们测定了来自西班牙和法国的分离株的编码序列。TOSV比其他经过充分研究的白蛉病毒（如裂谷热病毒）具有更高的多样性。
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