Ribeira Tiago, Veiros Iolanda, Nunes Renato, Martins Lília
Serviço de Medicina Física e de Reabilitação, Centro Hospitalar de Coimbra, Coimbra.
Acta Med Port. 2008 Nov-Dec;21(6):559-66. Epub 2009 Mar 24.
Spondylodiscitis is a rare cause of spinal cord lesion. Although this kind of infection is known to have a low incidence; it reflects cases of major clinical interest, since early diagnosis and treatment are determinant reducing morbi-mortality and in improving functional prognosis.
To analyse demographic and clinical data; the diagnostic investigations, the rehabilitation programme and the outcome in hospitalised patients.
The authors performed a retrospective, descriptive study. They reviewed the medical records of all hospitalised patients in Centro Hospitalar de Coimbra (CHC), between January 2002 and April 2007, with the diagnosis of spondylodiscitis and for which the cooperation of Physical Medicine and Rehabilitation was required.
Of the 28 hospitalised patients found, the mean age was 63.5 years (DP +/-15,6); 71% come from a rural environment. The average days of hospitalisation time was 76.6 days (DP +/- 34,2). The most frequent involved agents were Mycobacterium tuberculosis (21%), Staphylococcus aureus (14%) and Brucella mellitensis (14%). In 39% of the cases no agent was identified. The most common clinical manifestations were pain (92%) and neurological sings/symptoms (35%). Of the diagnostic investigations undertaken, MRI (85%), CT scan (67%), increased ESR (60%) and CRP (71%) were the most used. The lumbar spine was the region most frequently involved (67%). In 42% of the cases para-spinal soft-tissue and/or spinal canal were affected. The preferable treatment was the conservative one; there was a need for surgical approach only in two patients. The rising up of the patients constituted the main reason, why the cooperation of Physical Medicine and Rehabilitation was required. In 67% of de cases, the patients were advised to use orthosis and 64% started a rehabilitation programme. Of the 21 patients with a known outcome, 62% recovered completely.
The most frequent causative agent was Mycobacterium tuberculosis, having a significant role in spondylodiscitis in our country, attending to its high prevalence. As there is almost always a late diagnosis, a long pharmacological treatment and a slow rehabilitation, there has to be a high rate of suspicion and an early rehabilitation in order to diminish mortality and its economic costs. Physical Medicine and Rehabilitation has a prevailing role in the improvement of the functional prognosis in this disease.
脊椎椎间盘炎是脊髓病变的罕见病因。尽管已知这类感染发病率较低;但它反映了具有重大临床意义的病例,因为早期诊断和治疗对于降低发病率和死亡率以及改善功能预后起着决定性作用。
分析住院患者的人口统计学和临床数据、诊断检查、康复计划及治疗结果。
作者进行了一项回顾性描述性研究。他们查阅了2002年1月至2007年4月期间在科英布拉中心医院(CHC)住院的所有诊断为脊椎椎间盘炎且需要物理医学与康复科合作的患者的病历。
在找到的28例住院患者中,平均年龄为63.5岁(标准差±15.6);71%来自农村地区。平均住院天数为76.6天(标准差±34.2)。最常见的致病病原体为结核分枝杆菌(21%)、金黄色葡萄球菌(14%)和马尔他布鲁氏菌(14%)。39%的病例未查明病原体。最常见的临床表现为疼痛(92%)和神经体征/症状(35%)。在进行的诊断检查中,MRI(85%)、CT扫描(67%)、血沉升高(60%)和C反应蛋白升高(71%)是最常用的。腰椎是最常受累的部位(67%)。42%的病例椎旁软组织和/或椎管受到影响。首选治疗方法是保守治疗;仅两名患者需要手术治疗。患者起床活动是需要物理医学与康复科合作的主要原因。67%的病例建议患者使用矫形器,64%的患者开始康复计划。在已知治疗结果的21例患者中,62%完全康复。
最常见的致病病原体是结核分枝杆菌,鉴于其在我国的高流行率,在我国脊椎椎间盘炎中起重要作用。由于几乎总是诊断延迟、药物治疗时间长且康复缓慢,因此必须高度怀疑并尽早进行康复治疗,以降低死亡率及其经济成本。物理医学与康复科在改善该疾病的功能预后方面起着重要作用。