嗜软骨沃氏菌在卡氏棘阿米巴中对抗生素的敏感性
Antibiotic susceptibility of Waddlia chondrophila in Acanthamoeba castellanii amoebae.
作者信息
Goy Geneviève, Greub Gilbert
机构信息
Center for Research on Intracellular Bacteria, Institute of Microbiology, University Hospital Center and University of Lausanne, 1011 Lausanne, Switzerland.
出版信息
Antimicrob Agents Chemother. 2009 Jun;53(6):2663-6. doi: 10.1128/AAC.00046-09. Epub 2009 Mar 30.
Abstract
Waddlia chondrophila is an emerging cause of miscarriage in bovines and humans. Given the strict intracellular growth of this Chlamydia-like organism, its antibiotic susceptibility was tested by amoebal coculture, cell culture, and real-time PCR. W. chondrophila was susceptible to doxycycline and azithromycin but resistant to beta-lactams and fluoroquinolones.
摘要
嗜软骨瓦德菌是牛和人类流产的一个新出现病因。鉴于这种衣原体样生物体严格的细胞内生长特性，通过变形虫共培养、细胞培养和实时聚合酶链反应对其抗生素敏感性进行了检测。嗜软骨瓦德菌对多西环素和阿奇霉素敏感，但对β-内酰胺类和氟喹诺酮类耐药。
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