Federspil P
Universitäts-HNO-Klinik und -Poliklinik, Akazienweg 1, 66424 Homburg/Saar.
HNO. 2009 Apr;57(4):377-94. doi: 10.1007/s00106-009-1895-2.
In 1999 the following guidelines were elaborated by a consensus conference of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery with delegates of 10 further societies and complemented by a Delphi procedure. In 2002 and 2008 up-dates were performed by the members of the consensus conference, the chair of the study group of ENT infectiology of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery and the presidency of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery. The guidelines concern the antibiotic treatment of bacterial infections of the ears, nose and throat, taking the expected spectrum of pathogens, the microbiological and clinical efficacy and the containment of costs into consideration. After specification of the basic principles, the various infections with their causative pathogens and the antibiotics coming into question for therapy are tabulated and a differentiation is made between the antibiotic or the antibiotics of first choice and alternatives. The different dosages of oral and parenteral antibiotics for adults and children are indicated. In the appendix the different groups of antibiotics are characterized concerning their antibacterial spectrum and pharmacokinetics and in particular the differences between the older and newer representatives of the groups are pointed out.
1999年,德国耳鼻咽喉头颈外科学会与另外10个学会的代表共同召开了一次共识会议,制定了以下指南,并通过德尔菲法进行了补充。2002年和2008年,共识会议成员、德国耳鼻咽喉头颈外科学会耳鼻喉感染病学研究组组长以及德国耳鼻咽喉头颈外科学会主席对指南进行了更新。这些指南涉及耳、鼻、喉细菌感染的抗生素治疗,同时考虑了预期的病原体谱、微生物学和临床疗效以及成本控制。在明确基本原则后,将各种感染及其致病病原体以及可供治疗选择的抗生素制成表格,并区分出首选抗生素和替代抗生素。列出了成人和儿童口服及静脉用抗生素的不同剂量。附录中对不同类别的抗生素的抗菌谱和药代动力学进行了描述,特别指出了各类别中旧有和新型代表药物之间的差异。