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[线性B细胞表位预测]

[Linear B-cell epitope prediction].

作者信息

Davydov Ia I, Tonevitskiĭ A G

出版信息

Mol Biol (Mosk). 2009 Jan-Feb;43(1):166-74. doi: 10.1134/s0026893309010221.

DOI:10.1134/s0026893309010221
PMID:19334539
Abstract

Combination of sliding window method with physical properties scale of amino acids is a classical approach for linear B-cell epitope prediction. But it was shown that accuracy of these methods is poor. We reviewed classical and new algorithms of epitope prediction and present own implementation of one of them. The AAPPred software is available online at http://www.bioinf.ru/aappred/.

摘要

滑动窗口方法与氨基酸物理性质量表相结合是线性B细胞表位预测的经典方法。但已表明这些方法的准确性较差。我们综述了表位预测的经典算法和新算法，并展示了其中一种算法的自主实现。AAPPred软件可在http://www.bioinf.ru/aappred/在线获取。

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