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耐多药葡萄球菌和肠球菌的流行病学及耐药问题。

Epidemiological and resistance issues in multidrug-resistant staphylococci and enterococci.

作者信息

Leclercq R

机构信息

Department of Microbiology, CHU Côte de Nacre and EA 2128, University of Caen-Basse-Normandie, Caen, France.

出版信息

Clin Microbiol Infect. 2009 Mar;15(3):224-31. doi: 10.1111/j.1469-0691.2009.02739.x.

DOI:10.1111/j.1469-0691.2009.02739.x
PMID:19335370
Abstract

The spread of methicillin-resistant Staphylococcus aureus is continuous. The emergence of community-acquired methicillin-resistant S. aureus (CA-MRSA) was rapidly followed by its introduction into and dissemination in hospitals in countries where CA-MRSA prevalence is high. Vancomycin-resistant enterococci have recently been responsible for outbreaks in European hospitals in relation to dissemination of hospital-adapted isolates. Although new antimicrobials have been recently introduced into therapy to fight multidrug-resistant Gram-positive cocci, resistance to these compounds has already emerged in rare strains. This review presents recent data concerning the advance of our knowledge related to these problems.

摘要

耐甲氧西林金黄色葡萄球菌的传播一直在持续。社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)出现后,很快就在CA-MRSA流行率高的国家的医院中被引入并传播开来。耐万古霉素肠球菌最近在欧洲医院引发了与医院适应性菌株传播相关的疫情。尽管最近已将新的抗菌药物引入治疗以对抗多重耐药革兰氏阳性球菌,但在罕见菌株中已经出现了对这些化合物的耐药性。本综述介绍了有关我们在这些问题上知识进展的最新数据。

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