Goodman Jeremy, Becker Yolanda Tai
University of Alabama School of Medicine, Birmingham, Alabama, USA.
Curr Opin Organ Transplant. 2009 Feb;14(1):85-9. doi: 10.1097/MOT.0b013e328320a8ec.
Whole organ pancreas transplantation is the most durable cure for type 1 diabetes. Many advances have occurred that allow for long-term freedom from insulin and abrogation of the secondary complications of diabetes. However, pancreas allograft survival is dependant upon excellent technical success in the first month following transplantation.
It is clear that prevention of surgical complications has implications not only for graft and patient survival but also significantly impacts the financial impact following transplantation. Although complications can occur, early appropriate management can limit morbidity. In addition, when pancreas and kidney transplantation occur simultaneously, delayed treatment of pancreas complications can lead to kidney allograft loss.
This review concentrates on the diagnosis and management of early surgical complications following pancreas transplantation. The financial implications of surgical outcomes in pancreas transplantation are also discussed.
全器官胰腺移植是1型糖尿病最持久的治疗方法。已经取得了许多进展，可实现长期无需胰岛素治疗并消除糖尿病的继发并发症。然而，胰腺移植的存活取决于移植后第一个月出色的技术成功。
显然，预防手术并发症不仅对移植物和患者的存活有影响，而且对移植后的经济影响也有重大影响。虽然可能会出现并发症，但早期适当的管理可以限制发病率。此外，当胰腺和肾脏同时移植时，胰腺并发症的延迟治疗可能导致肾移植失败。
本综述集中讨论胰腺移植术后早期手术并发症的诊断和管理。还讨论了胰腺移植手术结果的经济影响。
