Réanimation Médicale;
Ther Clin Risk Manag. 2008 Dec;4(6):1375-9. doi: 10.2147/tcrm.s4110.
Three women were consecutively admitted to our medical intensive care unit for thyrotoxicosis after the ingestion of dietary pills accidentally containing high levels of thyroxin. These cases were observed during an outbreak in the Paris area. Despite similar blood levels of thyroid hormones, their clinical presentation and outcome were very different. One patient developed febrile confusion and died from malignant hyperthermia. The second one had progressive confusion requiring mechanical plasma exchange therapy and had a favorable outcome. The third one had very moderate symptoms. These exceptional observations raise several issues concerning diagnosis, physiopathology and treatment of thyrotoxicosis factitia.
三位女性因误食含有高浓度甲状腺素的膳食补充剂而相继被收住我院重症监护病房，诊断为甲状腺毒症。这些病例发生在巴黎地区的一次暴发疫情中。尽管她们的甲状腺激素血水平相似，但临床表现和结局却大不相同。一位患者出现发热性意识混乱，并死于恶性高热。第二位患者逐渐出现意识混乱，需要进行机械性血浆置换治疗，结局良好。第三位患者仅有非常轻微的症状。这些罕见的观察结果引发了一些关于假性甲状腺毒症的诊断、病理生理学和治疗的问题。
