Department of Mental Health, A.U.S.L. 4 L'Aquila, Italy.
Neuropsychiatr Dis Treat. 2008 Dec;4(6):1241-4. doi: 10.2147/ndt.s4066.
The diagnostic specificity of poor premorbid intelligence is controversial. We explored premorbid intelligence level in psychiatric patients with personality disorders, depressive disorders, bipolar disorders and schizophrenic disorders. 273 consecutively admitted patients and 81 controls were included in the study and tested with the 'Test di Intelligenza Breve', an Italian adaptation of the National Adult Reading Test. Significant differences between the clinical samples and the control subjects were found but not among the 4 clinical groups. The observation of premorbid IQ deficits in subjects with diagnoses other than schizophrenia suggests a common vulnerability diathesis, which is most likely to have a neurodevelopmental basis.
病前智力水平低对诊断的特异性存在争议。我们研究了伴有人格障碍、抑郁障碍、双相情感障碍和精神分裂症的精神科患者的病前智力水平。研究纳入了 273 例连续入院患者和 81 例对照，采用“短程智力测验”（一种意大利语改编的全国成人阅读测验）进行测试。在临床样本和对照组之间发现了显著差异，但在 4 个临床组之间没有差异。除精神分裂症以外的诊断患者存在病前智商缺陷，这提示存在共同的易感性素质，其很可能具有神经发育基础。
