Gyntelberg F, Brennan R, Holloszy J O, Schonfeld G, Rennie M J, Weidman S W
Am J Clin Nutr. 1977 May;30(5):716-20. doi: 10.1093/ajcn/30.5.716.
Exercise can lower fasting triglyceride levels (TG). This study was undertaken to determine whether the exercise-induced decrease in TG is the result of a negative caloric balance. Five subjects with primary type IV hyperlipoproteinemia were given diets comparable in composition to their usual diets. During one experimental period the subjects exercised while maintaining their usual caloric intakes. During another experimental period their caloric intake was increased to compensate for the exercise-induced increase in energy expenditure. The exercise, which consisted of 30 min of treadmill walking per day for 4 days, resulted in a progressive decrease in TG. The reduction in TG, which averaged 120 mg/100 ml, occurred regardless of whether or not the increase in caloric expenditure was compensated for by an increase in food intake. The decrease in TG was limited to the very low density lipoprotein fraction. No significant changes occurred in total plasma cholesterol concentration or in the distribution of cholesterol between the lipoprotein fractions. Fasting plasma glucagon concentration was constant for each individual and was unaffected by the exercise. The finding that exercise induces a decrease in TG despite increased food intake indicates that the TG lowering effect of exercise is not mediated by a negative caloric balance.
运动可降低空腹甘油三酯水平（TG）。本研究旨在确定运动引起的TG降低是否是热量负平衡的结果。选取了5名原发性IV型高脂蛋白血症患者，给予其成分与日常饮食相当的饮食。在一个实验阶段，受试者在维持日常热量摄入的同时进行运动。在另一个实验阶段，他们的热量摄入增加，以补偿运动引起的能量消耗增加。运动包括每天在跑步机上行走30分钟，共持续4天，结果导致TG逐渐降低。无论热量消耗的增加是否通过食物摄入量的增加来补偿，TG平均降低120mg/100ml。TG的降低仅限于极低密度脂蛋白部分。总血浆胆固醇浓度或脂蛋白部分之间胆固醇的分布没有显著变化。每个个体的空腹血浆胰高血糖素浓度保持恒定，且不受运动影响。尽管食物摄入量增加，但运动仍能降低TG，这一发现表明运动降低TG的作用不是由热量负平衡介导的。
