The state of peroxidation processes in the basal nuclei of the brain in conditions of an altered photoperiod.

The state of peroxidation processes in the basal ganglia (caudate nucleus, globus pallidus, nucleus accumbens, amygdalar complex) of the rat brain was studied in conditions of an altered photoperiod. The results showed that changes to the normal photoperiodicity led to metabolic changes in these brain structures. In conditions of constant light, the basal nuclei showed increased lipid and protein peroxidation processes, with increases in the intensity of fibrinolysis and proteolysis and decreases in the activities of antioxidant defense system enzymes. In conditions of constant darkness, there were changes in fibrinolytic and proteolytic processes which were in different directions in different structures, along with decreases in free-radical processes on the background of the accumulation of modified proteins.