Department of Surgrery, Messologi General Hospital, Messologi, Greece.
World J Emerg Surg. 2009 Apr 3;4:12. doi: 10.1186/1749-7922-4-12.
The aim of this study was to evaluate the risk factors of wound dehiscence and determine which of them can be reverted.
We retrospectively analyzed 3500 laparotomies. Age over 75 years, diagnosis of cancer, chronic obstructive pulmonary disease, malnutrition, sepsis, obesity, anemia, diabetes, use of steroids, tobacco use and previous administration of chemotherapy or radiotherapy were identified as risk factors
Fifteen of these patients developed wound dehiscence. Emergency laparotomy was performed in 9 of these patients. Patients who had more than 7 risk factors died.
It is important for the surgeon to know that wound healing demands oxygen consumption, normoglycemia and absence of toxic or septic factors, which reduces collagen synthesis and oxidative killing mechanisms of neutrophils. Also the type of abdominal closure may plays an important role. The tension free closure is recommended and a continuous closure is preferable. Preoperative assessment so as to identify and remove, if possible, these risk factors is essential, in order to minimize the incidence of wound dehiscence, which has a high death rate.
本研究旨在评估切口裂开的危险因素,并确定哪些因素可以逆转。
我们回顾性分析了 3500 例剖腹手术。年龄超过 75 岁、癌症诊断、慢性阻塞性肺疾病、营养不良、脓毒症、肥胖、贫血、糖尿病、使用类固醇、吸烟和以前接受化疗或放疗被确定为危险因素。
这些患者中有 15 例发生了切口裂开。其中 9 例患者行急诊剖腹手术。有超过 7 个危险因素的患者死亡。
外科医生必须了解到,伤口愈合需要消耗氧气、保持血糖正常和不存在有毒或感染性因素,这些因素会降低胶原蛋白合成和中性粒细胞的氧化杀伤机制。此外,腹部缝合方式也可能起着重要作用。建议采用无张力缝合,并优先采用连续缝合。术前评估以识别和尽可能消除这些危险因素至关重要,以尽量减少切口裂开的发生率,因为切口裂开的死亡率很高。