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An improved procedure for nucleoside synthesis using glycosyl trifluoroacetimidates as donors.

作者信息

Liao Jinxi, Sun Jiansong, Yu Biao

机构信息

Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.

出版信息

Carbohydr Res. 2009 May 26;344(8):1034-8. doi: 10.1016/j.carres.2009.03.010. Epub 2009 Mar 14.

DOI:10.1016/j.carres.2009.03.010
PMID:19342007
Abstract

Using glycosyl trifluoroacetimidates as donors and nitromethane (or acetonitrile) as solvent, silylation and subsequent glycosylation were realized in a 'one-pot' procedure to provide the corresponding nucleosides derivatives in high yields. [structure: see text].

摘要

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