Brandt Suzanne M, Swistel Alexander J, Rosen Paul Peter
Department of Pathology and Laboratory Medicine, New York Presbyterian Hospital-Weill Cornell Medical College, New York, NY 10065, USA.
Am J Surg Pathol. 2009 Jun;33(6):950-3. doi: 10.1097/PAS.0b013e31819c2628.
Invasive carcinoma in the axilla may arise from skin appendage glands or ectopic breast tissue or it may be a metastasis. Carcinomas of the skin adnexal glands and breast can be difficult to distinguish from each other as they often display the same patterns of growth. Tubular, cribriform, papillary, apocrine, mucinous, and adenoid cystic are histologic types of carcinoma seen in the breast and skin appendage glands. To our knowledge, secretory carcinoma, the most common form of mammary carcinoma in children, has not yet been described as a morphologic pattern of skin adnexal carcinoma, although we cannot exclude the possibility that such a case was reported with a different diagnosis. We report a case of a young girl with secretory carcinoma that seems to have arisen from skin appendage glands in the skin of the axilla in the absence of demonstrable ectopic breast tissue.
腋窝浸润性癌可能起源于皮肤附属器腺体或异位乳腺组织，也可能是转移瘤。皮肤附属器腺体癌和乳腺癌往往具有相同的生长模式，因此很难相互区分。管状、筛状、乳头状、大汗腺样、黏液性和腺样囊性是在乳腺和皮肤附属器腺体中可见的癌组织学类型。据我们所知，分泌性癌是儿童最常见的乳腺癌形式，尚未被描述为皮肤附属器癌的一种形态学模式，尽管我们不能排除曾有此类病例被误诊的可能性。我们报告一例年轻女孩的分泌性癌病例，该肿瘤似乎起源于腋窝皮肤的皮肤附属器腺体，且未发现明显的异位乳腺组织。
