Department of Psychiatry, Medical Faculty, Uludag University, Bursa, Turkey.
J Clin Exp Neuropsychol. 2009 Nov;31(8):999-1006. doi: 10.1080/13803390902776878. Epub 2009 Apr 3.
The aim of this study was to assess the validity and reliability of the 30-item Geriatric Depression Scale (GDS) as a screening tool for minor depression in poststroke patients.
Literate patients older than 18 years of age, diagnosed to have stroke, were eligible for the study. Standardized Mini Mental Status Examination (S-MMSE) and GDS were applied to all patients. The GDS was readministered 7 days later for retest reliability.
A total of 85 participants--49 nondepressed and 36 with minor depression--were eligible for the study. Cronbach's alpha coefficient was .89 in internal consistency analysis. The GDS scores were significantly higher (p < .001) in the depressed participants reflecting a high discriminant validity. The highest sum of sensitivity and specificity values of 1.44 (sensitivity = .69, specificity = .75) and 1.45 (sensitivity = .66, specificity = .79) were obtained for cutoff scores of 10/11 and 11/12, respectively. The area under receiver operating characteristics curve was .82. The test-retest reliability analysis revealed a high Pearson correlation coefficient (r = .75).
Our findings suggest that the 30-item GDS has high discriminant validity, internal consistency, and test-retest reliability and reasonably useful cutoff scores; thus it can be used as a screening tool for minor depression in the poststroke population.
本研究旨在评估 30 项老年抑郁量表（GDS）作为卒中后患者轻度抑郁筛查工具的有效性和可靠性。
纳入标准为年龄>18 岁、确诊卒中的有文化的患者。所有患者均接受标准化简易精神状态检查（S-MMSE）和 GDS 检查。7 天后对 GDS 进行重测以评估重测信度。
共有 85 名符合条件的参与者，其中 49 名无抑郁，36 名有轻度抑郁。内部一致性分析中 Cronbach's alpha 系数为 0.89。抑郁组的 GDS 评分显著升高（p<0.001），反映了较高的鉴别效度。截断值为 10/11 和 11/12 时，敏感性和特异性的总和最高，分别为 1.44（敏感性=0.69，特异性=0.75）和 1.45（敏感性=0.66，特异性=0.79）。受试者工作特征曲线下面积为 0.82。测试-重测信度分析显示 Pearson 相关系数高（r=0.75）。
我们的研究结果表明，30 项 GDS 具有较高的鉴别效度、内部一致性和测试-重测信度，且具有合理的截断值，因此可作为卒中后人群轻度抑郁的筛查工具。
