Swayne L C, Diehl W L, Brown T D, Hunter N J
Department of Diagnostic Radiology, Morristown Memorial Hospital, New Jersey 07960.
Clin Nucl Med. 1991 Sep;16(9):630-2. doi: 10.1097/00003072-199109000-00003.
A rare false-positive red blood cell scintigram occurred in a 49-year-old woman with two metastases from a primary adenocarcinoma of the sigmoid colon. Although the blood flow and static planar images were unremarkable, a 1-hour postinjection SPECT study showed a focus of increased activity in the inferior right lobe and a second photopenic focus in the dome. Following a trisegmentectomy, pathologic examination revealed the two metastases with no evidence of a hepatic hemangioma. Microscopy, however, showed a discrete area of nonspecific reactive changes (focal sinusoidal dilation and congestion) immediately adjacent to teh metastasis in the inferior right lobe. It is postulated that the SPECT focus of increased activity occurred secondary to the labeled blood pool within the area of sinusoidal dilation, rather than within the adjacent metastasis.
一名49岁患有乙状结肠原发性腺癌两处转移灶的女性出现了罕见的红细胞闪烁扫描假阳性。尽管血流和静态平面图像并无异常，但注射后1小时的SPECT研究显示右下叶有一个活性增加的病灶，穹窿部有第二个放射性缺损灶。在进行三段肝切除术后，病理检查发现两处转移灶，未发现肝血管瘤迹象。然而，显微镜检查显示右下叶转移灶紧邻处有一个离散的非特异性反应性改变区域（局灶性窦状扩张和充血）。据推测，SPECT活性增加的病灶是由于窦状扩张区域内的标记血池引起，而非相邻的转移灶。
