降低体重指数切点能更好地识别肥胖的脊髓损伤患者。
Lowering body mass index cutoffs better identifies obese persons with spinal cord injury.
机构信息
Department of Family Relations and Applied Human Nutrition, University of Guelph, Guelph, Ontario, Canada NIG 2W1.
出版信息
Spinal Cord. 2009 Oct;47(10):757-62. doi: 10.1038/sc.2009.33. Epub 2009 Apr 7.
STUDY DESIGN
Cross-sectional, non-experimental design.
OBJECTIVES
(1) Determine the sensitivity and specificity of the general population body mass index (BMI) cutoff for obesity (30 kg m(-2)) in a representative sample of persons with spinal cord injury (SCI); (2) develop a more sensitive BMI cutoff for obesity based on percentage of fat mass (%FM) and C-reactive protein (CRP).
SETTING
Ontario, Canada.
METHODS
A total of 77 community-dwelling adults with chronic SCI underwent anthropometric measures (%FM by bioelectrical impedance analysis, length, weight, BMI (kg m(-2))) and provided blood samples to determine CRP. Sensitivity and specificity analyses, piecewise regression, non-linear regression, and receiver-operator characteristic curves were used to determine new BMI cutoffs.
RESULTS
A BMI cutoff of 30 kg m(-2) failed to identify 73.9% of obese participants vs 26.1% at a lowered cutoff of 25 kg m(-2). BMI cutoffs based on risk levels of the %FM and CRP considered together ranged from 22.1 kg m(-2)-26.5 kg m(-2).
CONCLUSIONS
People with chronic SCI and BMI values >22 kg m(-2) should be considered as being at high risk for obesity and obesity-related chronic diseases.
SPONSORSHIP
Canadian Institutes of Health Research.
研究设计
横断面、非实验设计。
目的
（1）确定肥胖（30kg/m^2）的普通人群体重指数（BMI）切点在具有代表性的脊髓损伤（SCI）人群样本中的灵敏度和特异性；（2）根据体脂百分比（%FM）和 C 反应蛋白（CRP）开发更敏感的肥胖 BMI 切点。
地点
加拿大安大略省。
方法
共有 77 名居住在社区的慢性 SCI 成年人接受了人体测量学测量（生物电阻抗分析的 %FM、长度、体重、BMI（kg/m^2））并提供了血液样本以确定 CRP。使用灵敏度和特异性分析、分段回归、非线性回归和接收者操作特征曲线来确定新的 BMI 切点。
结果
BMI 切点为 30kg/m^2 未能识别 73.9%的肥胖参与者，而降低的切点为 25kg/m^2 时为 26.1%。综合考虑 %FM 和 CRP 的风险水平的 BMI 切点范围为 22.1kg/m^2-26.5kg/m^2。
结论
BMI 值大于 22kg/m^2 的慢性 SCI 患者应被视为肥胖和肥胖相关慢性疾病的高风险人群。
资助
加拿大卫生研究院。
Zotero 插件