Erlandsson Kjell, Kacperski Krzysztof, van Gramberg Dean, Hutton Brian F
Institute of Nuclear Medicine, University College London, Dean van Foundation Trust, London, UK.
Phys Med Biol. 2009 May 7;54(9):2635-49. doi: 10.1088/0031-9155/54/9/003. Epub 2009 Apr 8.
D-SPECT (Spectrum Dynamics, Israel) is a novel SPECT system for cardiac perfusion studies. Based on CZT detectors, region-centric scanning, high-sensitivity collimators and resolution recovery, it offers potential advantages over conventional systems. A series of measurements were made on a beta-version D-SPECT system in order to evaluate its performance in terms of energy resolution, scatter fraction, sensitivity, count rate capability and resolution. Corresponding measurements were also done on a conventional SPECT system (CS) for comparison. The energy resolution of the D-SPECT system at 140 keV was 5.5% (CS: 9.25%), the scatter fraction 30% (CS: 34%), the planar sensitivity 398 s(-1) MBq(-1) per head ((99m)Tc, 10 cm) (CS: 72 s(-1) MBq(-1)), and the tomographic sensitivity in the heart region was in the range 647-1107 s(-1) MBq(-1) (CS: 141 s(-1) MBq(-1)). The count rate increased linearly with increasing activity up to 1.44 M s(-1). The intrinsic resolution was equal to the pixel size, 2.46 mm (CS: 3.8 mm). The average reconstructed resolution using the standard clinical filter was 12.5 mm (CS: 13.7 mm). The D-SPECT has superior sensitivity to that of a conventional system with similar spatial resolution. It also has excellent energy resolution and count rate characteristics, which should prove useful in dynamic and dual radionuclide studies.
D-SPECT（以色列光谱动力学公司）是一种用于心脏灌注研究的新型单光子发射计算机断层扫描（SPECT）系统。基于碲锌镉（CZT）探测器、以区域为中心的扫描、高灵敏度准直器和分辨率恢复技术，它相较于传统系统具有潜在优势。为了评估其在能量分辨率、散射分数、灵敏度、计数率能力和分辨率方面的性能，在一台beta版D-SPECT系统上进行了一系列测量。同时也在一台传统SPECT系统（CS）上进行了相应测量以作比较。D-SPECT系统在140keV时的能量分辨率为5.5%（CS为9.25%），散射分数为30%（CS为34%），平面灵敏度为每头398 s(-1) MBq(-1)（(99m)Tc，10 cm）（CS为72 s(-1) MBq(-1)），心脏区域的断层灵敏度在647 - 1107 s(-1) MBq(-1)范围内（CS为141 s(-1) MBq(-1)）。计数率随活度增加呈线性增加，直至1.44 M s(-1)。固有分辨率等于像素大小，为2.46 mm（CS为3.8 mm）。使用标准临床滤波器的平均重建分辨率为12.5 mm（CS为13.7 mm）。D-SPECT在空间分辨率相似的情况下，其灵敏度优于传统系统。它还具有出色的能量分辨率和计数率特性，这在动态和双放射性核素研究中应会很有用。
