Imperiale Alessio, Moser Thomas, Ben-Sellem Dorra, Mertz Luc, Gangi Afshin, Constantinesco André
Service de Biophysique et de Médecine Nucléaire, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Clin Nucl Med. 2009 Mar;34(3):184-8. doi: 10.1097/RLU.0b013e3181966de6.
Osteoblastoma (OB) and osteoid osteoma (OO) are benign bone-forming tumors frequently involving vertebrae and long bones of the extremities. Because of their similar histopathological features, distinction between OB and OO is mostly based on size criteria. CT and MRI represent the cornerstone of noninvasive diagnostic procedures, as they provide excellent morphologic details and often obviate the need for confirmatory biopsy. Bone scan is a complementary, highly sensitive functional technique particularly useful for detection of vertebral OO. F-18 FDG PET/CT could have potentiality in diagnosis and post therapeutic evaluation of patients with OB and OO. We report MRI and dynamic F-18 FDG PET/CT results obtained before radiofrequency or laser ablation from 3 patients with an OB of the right L5 pedicle, an OB of the left talus and an OO of the right acetabulum. Both patients with OB underwent posttherapeutic evaluation to confirm the effectiveness of percutaneous radiofrequency ablation.
骨母细胞瘤(OB)和骨样骨瘤(OO)是常见的良性成骨性肿瘤,常累及椎骨和四肢长骨。由于它们具有相似的组织病理学特征,OB和OO的区分主要基于大小标准。CT和MRI是非侵入性诊断程序的基石,因为它们能提供出色的形态学细节,且常常无需进行确诊性活检。骨扫描是一种辅助性的、高度敏感的功能性技术,对检测椎体OO特别有用。F-18 FDG PET/CT在OB和OO患者的诊断及治疗后评估中可能具有潜力。我们报告了3例患者在接受射频或激光消融治疗前的MRI及动态F-18 FDG PET/CT结果,这3例患者分别为右侧L5椎弓根骨母细胞瘤、左侧距骨骨母细胞瘤和右侧髋臼骨样骨瘤。2例骨母细胞瘤患者均接受了治疗后评估,以确认经皮射频消融的有效性。