Sarmiento J Manuel, Chan Julie L, Cohen Justin D, Mukherjee Debraj, Chu Ray M
Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, USA.
Cureus. 2019 Mar 12;11(3):e4239. doi: 10.7759/cureus.4239.
Osteoid osteoma is a benign primary bone tumor of unknown etiology that occurs most commonly in males during adolescence and early adulthood. Osteoid osteoma affects the spine in 20% of cases, and may cause spinal deformity, stiffness, and pain that may sometimes be worst at night. We present a novel description of a partial laminectomy with cement augmentation after resection of an osteoid osteoma. A 22-year-old male with a past medical history of Hodgkin's lymphoma status post chemotherapy and radiation to the mediastinum, and right hip osteoblastoma treated with surgery and radiofrequency ablation presented with low back pain for five years with a recent onset of severe radicular symptoms. The pain was described as shooting and radiating laterally down the right leg to the mid-calf without bowel or bladder incontinence. He has a known right L5 laminar sclerotic lesion measuring 11 x 10 mm causing neuroforaminal narrowing and it kept increasing in size despite previous treatment with stereotactic radiosurgery and radiofrequency ablation. This lesion was metabolically active on positron emission tomography-computed tomography (PET-CT) imaging. His pain was worsening and was refractory to physical therapy, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin, and radiation therapy. A right L5 partial laminectomy was performed to resect the abnormality in an en-bloc fashion. The lesion did not involve the inner cortex of the bone. Lamina reconstruction was achieved with bone cement augmentation for the preservation of vertebral column strength. Pathology was consistent with osteoid osteoma with marrow edema. Microscopic findings include bony trabeculae associated with prominent rimming and hypercellular fibroblastic stroma. No nuclear atypia, necrosis or appreciable mitotic activity was observed. The patient remains neurologically intact with significantly improved radicular symptoms and low back pain. Osteoid osteoma of the lamina may be resected using a partial laminectomy and cement augmentation done to preserve the integrity of the posterior ligamentous complex, prevent potential fracture of the pars interarticularis, and avoid the need for lumbar fusion in younger patients in whom this pathology is commonly found.
骨样骨瘤是一种病因不明的原发性良性骨肿瘤,最常见于青春期和成年早期的男性。骨样骨瘤在20%的病例中累及脊柱,可导致脊柱畸形、僵硬和疼痛,有时夜间疼痛最为严重。我们介绍了一种在切除骨样骨瘤后进行骨水泥强化的部分椎板切除术的新方法。一名22岁男性,既往有霍奇金淋巴瘤病史,接受过纵隔化疗和放疗,右髋骨母细胞瘤接受过手术和射频消融治疗,出现腰痛5年,近期出现严重的神经根症状。疼痛被描述为刺痛,沿右腿外侧向下放射至小腿中部,无大小便失禁。他有一个已知的右侧L5椎板硬化病变,大小为11×10mm,导致神经孔狭窄,尽管先前接受了立体定向放射外科和射频消融治疗,但其大小仍不断增加。该病变在正电子发射断层扫描-计算机断层扫描(PET-CT)成像上代谢活跃。他的疼痛不断加重,对物理治疗、非甾体抗炎药(NSAIDs)、阿司匹林和放射治疗均无效。进行了右侧L5部分椎板切除术,以整块切除异常组织。病变未累及骨的内皮质。通过骨水泥强化实现椎板重建,以保留脊柱强度。病理结果与伴有骨髓水肿的骨样骨瘤一致。显微镜下表现包括与明显边缘和高细胞性纤维母细胞基质相关的骨小梁。未观察到核异型性、坏死或明显的有丝分裂活性。患者神经功能保持完整,神经根症状和腰痛明显改善。椎板骨样骨瘤可通过部分椎板切除术和骨水泥强化进行切除,以保留后韧带复合体的完整性,防止关节突间部潜在骨折,并避免在常见这种病理情况的年轻患者中进行腰椎融合。