Subbiah M T, Dicke B
Atherosclerosis. 1977 May;27(1):59-64. doi: 10.1016/0021-9150(77)90024-7.
The effect of short-term (6 months) administration of conjugated equine estrogen (Premarin) on content and composition of the aortic sterols in male shite Carneau pigeons while they were on a cholesterol-free grain diet was investigated. Estrogen treatment resulted in a 38% increase (P less than 0.05) in free sterol concentration, with a 28.8% concomitant decrease (P less than 0.05) in the percent of cholesteryl esters. The total sterol concentration remained unchanged. This finding suggests that estrogens might influence the synthetic or hydrolytic (or both) processes that control the concentration of cholesteryl esters in the aorta. Fatty acid composition of steryl esters did not change significantly. The cholesterol content of plasma showed a mild reduction (14%) whereas the triglycerides increased significantly (30%).
研究了在无胆固醇谷物饮食条件下，给雄性白卡诺鸽短期（6个月）服用结合马雌激素（倍美力）对其主动脉甾醇含量和组成的影响。雌激素处理使游离甾醇浓度增加了38%（P<0.05），同时胆固醇酯百分比相应降低了28.8%（P<0.05）。总甾醇浓度保持不变。这一发现表明，雌激素可能会影响控制主动脉中胆固醇酯浓度的合成或水解（或两者）过程。甾醇酯的脂肪酸组成没有显著变化。血浆中的胆固醇含量略有降低（14%），而甘油三酯显著增加（30%）。
