Schmitt Natalie M, Schmitt Jochen, Dören Martina
Public Health Department Sächsische Schweiz - Osterzgebirge, Dippoldiswalde, Germany.
Maturitas. 2009 May 20;63(1):34-8. doi: 10.1016/j.maturitas.2009.03.002. Epub 2009 Apr 7.
Osteoporosis causes an increase in bone fragility. Its clinical significance mainly refers to (hip) fractures secondary to (low or moderate) trauma. In Europe and North America about 6% of men and 21% of women aged 50-84 years are classified to have osteoporosis. Although it is well accepted that exercise is essential for the management of osteoporosis, the exact role of physical activity in the primary and secondary prevention of osteoporotic fractures is still controversial.
The MEDLINE database and reference lists of selected publications were systematically searched for randomized controlled trials and prospective cohort studies, respectively, published since January 2000 regarding the association of physical activity and osteoporosis in postmenopausal women.
Two prospective cohort studies indicate the clinical relevance of this association by showing an inverse relationship between physical activity and the risk of hip fracture. There is convincing evidence that physical activity effectively slows bone loss in postmenopausal women in a dose-dependent manner. Exercise programs may increase bone mineral density.
In order to maximize the goals of public health most effective, individually adapted, intense, high impact exercise programs are needed. However, they may be complicated to communicate and adherence on the population level may be hard to achieve. These programs must be weighed against popular and applicable existing programs (e.g. aerobic classes, Tai Chi, and walking) which appear to be easier to adhere to but appear to be less effective in the prevention of osteoporotic fractures in the individual postmenopausal women.
骨质疏松会导致骨脆性增加。其临床意义主要指(低或中度)创伤继发的(髋部)骨折。在欧洲和北美,50 - 84岁的男性中约6%、女性中约21%被归类为患有骨质疏松症。尽管人们普遍认为运动对骨质疏松症的管理至关重要,但体育活动在骨质疏松性骨折一级和二级预防中的具体作用仍存在争议。
分别系统检索MEDLINE数据库以及所选出版物的参考文献列表,以查找自2000年1月以来发表的关于绝经后女性体育活动与骨质疏松症关联的随机对照试验和前瞻性队列研究。
两项前瞻性队列研究通过显示体育活动与髋部骨折风险之间的负相关关系,表明了这种关联的临床相关性。有令人信服的证据表明,体育活动能以剂量依赖的方式有效减缓绝经后女性的骨质流失。运动计划可能会增加骨密度。
为了最有效地实现公共卫生目标,需要制定最有效、个体化适配、高强度、高冲击力的运动计划。然而,这些计划可能在宣传方面较为复杂,且在人群层面难以实现依从性。必须将这些计划与现有的流行且适用的计划(如有氧运动课程、太极拳和散步)进行权衡,后者似乎更易于坚持,但在预防个体绝经后女性骨质疏松性骨折方面似乎效果较差。