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英国透析患者的种族、社会经济地位与临床实践指南标准的达成情况

Ethnicity, socioeconomic status, and attainment of clinical practice guideline standards in dialysis patients in the United kingdom.

作者信息

Udayaraj Udaya P, Ben-Shlomo Yoav, Roderick Paul, Steenkamp Retha, Ansell David, Tomson Charles R V, Caskey Fergus J

机构信息

UK Renal Registry, Southmead Hospital, Southmead Road, Bristol, BS10 5NB, UK.

出版信息

Clin J Am Soc Nephrol. 2009 May;4(5):979-87. doi: 10.2215/CJN.06311208. Epub 2009 Apr 8.

Abstract

BACKGROUND AND OBJECTIVES

The role of socioeconomic status (SES) and its contribution to ethnic differences in standards attainment among dialysis patients is not known.

DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We examined associations between area- level SES (Townsend index) and ethnicity (white, black, South Asian) and standards attainment in 14,117 incident dialysis patients (1997-2004) in the UK.

RESULTS

Deprived patients were less likely to achieve hemoglobin (Hb) > or = 10 g/dl (trend P < 0.001) but not after controlling for patient and center characteristics (trend P = 0.1). There was no association with hemodialysis dose and parathyroid hormone (PTH) standard but deprived patients had better attainment of phosphate (PO4) <5.6 mg/dl, calcium (Ca) and Calcium-phosphate (CaPO4) standard (e.g., most deprived versus least deprived adjusted odds ratio [OR] 1.25, 95% confidence intervals [CI] 1.12, 1.38). There was no association with SES using a lower limit for PO4 (3.5 - 5.5 mg/dl). Compared with Whites, Blacks had lower attainment of Hb (adjusted OR 0.57, 95% CI 0.45, 0.71) and PTH standards (adjusted OR 0.27, 95% CI 0.22, 0.33) but better attainment of PO4 and CaPO4, while South Asians experienced better or comparable outcomes for most standards except Ca and PTH.

CONCLUSIONS

There was no evidence of socioeconomic inequity in standards attainment or a consistent pattern of inequity by ethnic group. The lower attainment of some standards in ethnic minorities may reflect biologic differences rather than ethnicity-related inequity of care.

摘要

背景与目的

社会经济地位(SES)在透析患者达标情况中的作用及其对种族差异的影响尚不清楚。

设计、地点、参与者与测量方法:我们研究了英国14117例新发透析患者(1997 - 2004年)中地区层面的SES(汤森指数)与种族(白人、黑人、南亚人)以及达标情况之间的关联。

结果

贫困患者血红蛋白(Hb)≥10 g/dl的达标可能性较小(趋势P < 0.001),但在控制患者和中心特征后则不然(趋势P = 0.1)。SES与血液透析剂量和甲状旁腺激素(PTH)达标情况无关,但贫困患者在磷酸盐(PO4)<5.6 mg/dl、钙(Ca)和钙磷(CaPO4)达标方面表现更好(例如,最贫困组与最不贫困组调整后的优势比[OR]为1.25,95%置信区间[CI]为1.12, 1.38)。使用较低的PO4下限(3.5 - 5.5 mg/dl)时,SES与之无关。与白人相比,黑人的Hb达标率较低(调整后的OR为0.57,95% CI为0.45, 0.71)以及PTH达标率较低(调整后的OR为0.27,95% CI为0.22, 0.33),但PO4和CaPO4达标情况较好,而南亚人在大多数达标情况方面表现更好或相当,除了Ca和PTH。

结论

没有证据表明在达标情况方面存在社会经济不平等,也没有按种族群体呈现出一致的不平等模式。少数族裔在某些达标情况上较低可能反映了生物学差异而非与种族相关的护理不平等。

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